Self-referencing fiber optic particle plasmon resonance sensing system for real-time biological monitoring

Wu, Chin-Wei; Chiang, Chao-Lung; Chen, Chien‐Hsing; Chiang, Chung-Sheng; Wang, Chih-To; Chau, Lai-Kwan

doi:10.1016/j.talanta.2015.08.047

Cited by 30 publications

(27 citation statements)

References 32 publications

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“…Gold nanoparticles (AuNPs) were synthesized following a previously reported procedure [ 5 , 52 ]. An aqueous solution of HAuCl 4 solution (0.88 mM, 50 mL) was heated to boiling with vigorous stirring for about 15 min.…”

Section: Methodsmentioning

confidence: 99%

“…Then the fiber end faces were polished to an optically smooth surface to increase the transmission efficiency. Such partially unclad fibers after modification with AuNPs were used as the sensing fibers [ 52 ]. Before modification with AuNPs on the sensing window, the partially unclad fibers were cleaned by a mixture of H 2 SO 4 and H 2 O 2 with volume ratio of 3:2.…”

Section: Methodsmentioning

confidence: 99%

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Effect of Surface Coverage of Gold Nanoparticles on the Refractive Index Sensitivity in Fiber-Optic Nanoplasmonic Sensing

Chen

Chiang

et al. 2018

Sensors

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A simple theoretical model was developed to analyze the extinction spectrum of gold nanoparticles (AuNPs) on the fiber core and glass surfaces in order to aid the determination of the surface coverage and surface distribution of the AuNPs on the fiber core surface for sensitivity optimization of the fiber optic particle plasmon resonance (FOPPR) sensor. The extinction spectrum of AuNPs comprises of the interband absorption of AuNPs, non-interacting plasmon resonance (PR) band due to isolated AuNPs, and coupled PR band of interacting AuNPs. When the surface coverage is smaller than 12.2%, the plasmon coupling effect can almost be ignored. This method is also applied to understand the refractive index sensitivity of the FOPPR sensor with respect to the non-interacting PR band and the coupled PR band. In terms of wavelength sensitivity at a surface coverage of 18.6%, the refractive index sensitivity of the coupled PR band (205.5 nm/RIU) is greater than that of the non-interacting PR band (349.1 nm/RIU). In terms of extinction sensitivity, refractive index sensitivity of the coupled PR band (−3.86/RIU) is similar to that of the non-interacting PR band (−3.93/RIU). Both maximum wavelength and extinction sensitivities were found at a surface coverage of 15.2%.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Effect of Surface Coverage of Gold Nanoparticles on the Refractive Index Sensitivity in Fiber-Optic Nanoplasmonic Sensing

Chen

Chiang

et al. 2018

Sensors

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“…The cost of commercial SPRs varies from $10,000 to $5,000,000, and the refractive index resolution ranges from 10 −5 RIU (refractive index unit) to 10 −7 RIU. Many optical-fiber based SPRs have been studied intensively in the literature [13][14][15]. The structure of these devices is relatively simple.…”

Section: Introductionmentioning

confidence: 99%

Angle-Scanning Surface Plasmon Resonance System with 3D Printed Components for Biorecognition Investigation

Zhang

Settu

Liu

2018

Advances in Condensed Matter Physics

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Surface plasmon resonance (SPR) is a real-time, label-free, and high-sensitive detection technology. SPR has been widely used in many applications such as biomolecular interaction analysis, environmental monitoring, and medical diagnostics. However, conventional SPR sensor systems usually require expensive equipment and complicated optics. In this paper, we have demonstrated a rapid prototyping of angle-scanning SPR for bioanalytical investigation. Rapid prototyping was attained by utilizing the FDM (fused deposition modeling) based 3D (three-dimensional) printing technology. Two rotating platforms were employed to drive the laser source and photodiode, respectively. A temperature regulation unit was incorporated to maintain the system temperature in order to reduce the temperature effect. The proposed SPR rapid prototyping yielded a refractive index resolution of 6.4×10 −6 RIU (refractive index unit), and the biotin-avidin system validated the kinetics parameters measurement capability. The obtained results indicated that the FDM 3D printing has great potential for developing rapid-prototyping SPR system.

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“…Although the system has employed the low sensitivity of the FP mode to temperature variations, other factors may affect the sensing results, including mass transport. Another approach based on a fiber optic particle plasmon resonance was proposed, employing two plastic-silica fiber optics (with core and cladding diameters of 400 μm and 430 μm, respectively) as sensing and reference channels 8 . The metal nanoparticles were anchored on an unclad sensing fiber of 20 mm sensing window, whereas the other unclad fiber optic was used as a reference channel.…”

Section: Introductionmentioning

confidence: 99%

Improved method for estimating adlayer thickness and bulk RI change for gold nanocrescent sensors

Abumazwed

Kubo

Tanaka

et al. 2018

Sci Rep

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This paper presents a novel method employing the maximum likelihood estimation (MLE) technique alongside a nonlinear sensor response model to improve and extract more quantitative sensing results for localized surface plasmon resonance biosensors. The nonlinear response model treats the sensor response as a nonlinear function of the biomolecular adlayer thickness. This method makes use of the multiple resonance characteristic of nanocrescent structures in order to estimate the adlayer thickness and bulk refractive index (RI) change. Nanoimprint lithography is used here to fabricate the nanostructures. The finite element method (FEM) is used to model the nanocrescents and numerically validate the nonlinear-MLE method. Comparing to the established linear model, the proposed nonlinear-MLE method achieves 75% improvement in the limit of detection based on the estimated adlayer thickness and improves the bulk RI resolution by two orders of magnitude.

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Self-referencing fiber optic particle plasmon resonance sensing system for real-time biological monitoring

Cited by 30 publications

References 32 publications

Effect of Surface Coverage of Gold Nanoparticles on the Refractive Index Sensitivity in Fiber-Optic Nanoplasmonic Sensing

Effect of Surface Coverage of Gold Nanoparticles on the Refractive Index Sensitivity in Fiber-Optic Nanoplasmonic Sensing

Angle-Scanning Surface Plasmon Resonance System with 3D Printed Components for Biorecognition Investigation

Improved method for estimating adlayer thickness and bulk RI change for gold nanocrescent sensors

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