Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

Amado, Leonilde; Ferreira, Nuno; Miranda, Vasco; Meireles, Patrícia; Povera, Verónica; Ferreira, Rosa Cristina Moutinho; Fazendeiro-Matos, João; Teixeira, Laetitia; Paúl, Constança; Santos-Silva, Alice; Costa, Elı́sio

doi:10.1111/jorc.12127

Cited by 10 publications

(11 citation statements)

References 40 publications

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“…21 This study showed that 15.7% of the patients considered themselves as non-adherent to medication. This prevalence is slightly higher than that found in a previous study by our group, 22 in which a prevalence of self-reported non-adherence to medicines was found in 10.7% of the patients, using the Morisky-Green-Levine Measure Treatment Adherence (MTA) scale. In this previous study, a negative association between MTA score and blood pressure and triglyceride serum levels was found.…”

Section: Discussioncontrasting

confidence: 68%

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End-stage renal disease adherence questionnaire: translation and validation to the portuguese language

Poveda

Amado²,

Filgueiras³

et al. 2016

Renal Failure

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Non-adherence to medical plans is recognized as an important problem in dialysis patients, since it has been associated with increased morbidity and mortality, resulting in disproportionately high costs of care. The success of renal replacement therapy depends on the adherence of patients to the different aspects of the therapeutic strategy, which includes a complex drug regimen involving a wide variety of drugs and doses, several prescribed dialysis sessions with different durations, dietetic recommendations and restriction of fluid intake. In this work, we aimed to translate and validate a previously described self-reported end-stage renal disease questionnaire (ESRD-AQ) to the Portuguese language (PESRD-AQ). After ESRD-AQ translation, a validation was performed by experts and by using a cohort of 185 Portuguese dialysis patients. PESRD-AQ reliability analysis showed strong test-retest stability across all items, with an intra-class correlation of 0.931. The average of the item-level content validity index by experts for the 46 items was 0.98, ranging from 0.94 to 1. Moreover, we found that PESRD-AQ scores indicative of non-adherence were associated with alterations in some biological and biochemical markers of non-adherence, including interdialytic weight gain. In conclusion, our results showed that PESRD-AQ, which presented an acceptable reliability and validity, is a valid tool to be used for adherence evaluation by Portuguese-speaking dialysis patients.

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Section: Discussioncontrasting

confidence: 68%

“…The overall adherence score is obtained by summing the responses of questions number 14, 17, 18, 26, 31, and 46, higher punctuation indicated better adherence behavior. Furthermore, questions 11,12,22,23,32,33,41, and 42 measure patients' knowledge and perceptions about treatment. 18…”

Section: Methodsmentioning

confidence: 99%

End-stage renal disease adherence questionnaire: translation and validation to the portuguese language

Poveda

Amado²,

Filgueiras³

et al. 2016

Renal Failure

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“…Multiple chronic diseases and polypharmacy, the coprescription of several drugs, are highly prevalent in older persons. 16 – 18 There is evidence that nonadherence increases with the number of chronic diseases and drugs. The management of chronic diseases required a continuous psychological adaptation and behavioral reorganization that may lead to significant changes with respect to therapeutic indications.…”

Section: Introductionmentioning

confidence: 99%

Interventional tools to improve medication adherence: review of literature

Costa

Giardini

Savin

et al. 2015

PPA

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Medication adherence and persistence is recognized as a worldwide public health problem, particularly important in the management of chronic diseases. Nonadherence to medical plans affects every level of the population, but particularly older adults due to the high number of coexisting diseases they are affected by and the consequent polypharmacy. Chronic disease management requires a continuous psychological adaptation and behavioral reorganization. In literature, many interventions to improve medication adherence have been described for different clinical conditions, however, most interventions seem to fail in their aims. Moreover, most interventions associated with adherence improvements are not associated with improvements in other outcomes. Indeed, in the last decades, the degree of nonadherence remained unchanged. In this work, we review the most frequent interventions employed to increase the degree of medication adherence, the measured outcomes, and the improvements achieved, as well as the main limitations of the available studies on adherence, with a particular focus on older persons.

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“…The lack of health management in CKD patients generates high levels of triglycerides and high blood pressure, which increases the risk of developing cardiovascular diseases (Amado et al, 2015; Luis et al, 2016). Life habits are modifiable elements, and these habits must be emphasized to achieve effective health management.…”

Section: Introductionmentioning

confidence: 99%

Ineffective Health Management in Hemodialysis Patients: Diagnostic Accuracy Study

et al. 2018

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This study analyzed the accuracy of clinical indicators of ineffective health management in hemodialysis patients. A diagnostic accuracy study was performed in 200 chronic kidney disease patients undergoing hemodialysis during the first half of 2015. Measures of sensitivity and specificity were calculated using latent class analysis. Ineffective health management was present in 66.28% of patients. Accurate clinical indicators included expressed nonadherence to treatment, daily life choices ineffective to achieve health goals, expression of difficulty with prescribed regimens, inappropriate use of medicines, lack of expression of willingness to control the disease, irregular attendance of dialysis sessions, and infection. Hemodialysis may trigger a set of clinical indicators that predict the presence of ineffective health management. This knowledge provides evidence to clinical practices for hemodialysis patients and contributes to the best clinical performance of nurse practitioners.

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Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

Cited by 10 publications

References 40 publications

End-stage renal disease adherence questionnaire: translation and validation to the portuguese language

End-stage renal disease adherence questionnaire: translation and validation to the portuguese language

Interventional tools to improve medication adherence: review of literature

Ineffective Health Management in Hemodialysis Patients: Diagnostic Accuracy Study

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