Sellar Defect Reconstruction with Vascularized Superior Turbinate Mucosal Flaps in Endonasal Endoscopic Transsellar Approach

Kutlay, Murat; Durmaz, Ozan; Kirik, Alparslan; Yaşar, Soner; Özer, Işıl; Ezgü, Mehmet Can; Kural, Cahit; Temız, Cüneyt; Durmaz, Abdullah; Daneyemez, Mehmet; İzci, Yusuf

doi:10.1016/j.wneu.2019.09.082

“…However, the problem of skull base reconstruction and cerebrospinal fluid in transnasal neuroendoscopic surgery has always been one of the difficult problems for neurosurgeons. With the continuous efforts of neurosurgeons to study various skull base reconstruction techniques, the incidence of cerebrospinal fluid leakage has been significantly improved[ 16 , 19 ], including vascular pedicled mucosal flap technique[ 27 - 30 ], artificial dura replacement material[ 31 - 32 ], or multi-layer reconstruction of autologous fat and fascia lata[ 16 , 33 ]. It has been reported that the incidence of cerebrospinal fluid leakage using the nasal septum pedicled mucosal flap technique is less than 5%[ 16 ].…”

Section: Discussionmentioning

confidence: 99%

“In situ bone flap” combined with vascular pedicled mucous flap to reconstruction of skull base defect

Qian,

Chen,

Zhang

et al. 2023

World J Clin Cases

1

0

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Time series analysis is a valuable tool in epidemiology that complements the classical epidemiological models in two different ways: Prediction and forecast. Prediction is related to explaining past and current data based on various internal and external influences that may or may not have a causative role. Forecasting is an exploration of the possible future values based on the predictive ability of the model and hypothesized future values of the external and/or internal influences. The time series analysis approach has the advantage of being easier to use (in the cases of more straightforward and linear models such as Auto-Regressive Integrated Moving Average). Still, it is limited in forecasting time, unlike the classical models such as Susceptible-Exposed-Infectious-Removed. Its applicability in forecasting comes from its better accuracy for short-term prediction. In its basic form, it does not assume much theoretical knowledge of the mechanisms of spreading and mutating pathogens or the reaction of people and regulatory structures (governments, companies, etc. ). Instead, it estimates from the data directly. Its predictive ability allows testing hypotheses for different factors that positively or negatively contribute to the pandemic spread; be it school closures, emerging variants, etc. It can be used in mortality or hospital risk estimation from new cases, seroprevalence studies, assessing properties of emerging variants, and estimating excess mortality and its relationship with a pandemic.

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“…At present, EET approach is the safest and rapid way to manage a patient with pituitary macroadenoma associated with apoplexy. [7,11,14] In addition, surgical intervention, when necessary, should be performed as soon as possible as it is associated with better visual outcome. Although emergent EET approach is the gold standard for the surgical treatment of pituitary apoplexy, the surgical technique is not different than the classical pituitary adenoma.…”

Section: Discussionmentioning

confidence: 99%

“…At present, EET approach is the safest and rapid way to manage a patient with pituitary macroadenoma associated with apoplexy. [ 7 , 11 , 14 ] In addition, surgical intervention, when necessary, should be performed as soon as possible as it is associated with better visual outcome.…”

Section: Discussionmentioning

confidence: 99%

“…Knosp grading system was used to categorize tumor extension and degree of cavernous sinus invasion. [10,11] Resection rates were defined as: Total resection (when no remaining tumor is observed on early MRI scans), subtotal resection (more than 80% of tumor resection compared with preoperative imaging), and partial resection (< 80%). [7] Visual acuity and visual field defects were evaluated in patients with visual disturbances, using computerized visual field testing preoperatively and 3 months after surgery.…”

Section: Methodsmentioning

confidence: 99%

“…Knosp grading system was used to categorize tumor extension and degree of cavernous sinus invasion. [ 10 , 11 ] Resection rates were defined as: Total resection (when no remaining tumor is observed on early MRI scans), subtotal resection (more than 80% of tumor resection compared with preoperative imaging), and partial resection (< 80%). [ 7 ]…”

Section: Methodsmentioning

confidence: 99%

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