Semana da conscientização sobre a importânciado ácido fólico

Abstract

RESUMONa primeira semana de outubro, a Associação Brasileira de Epilepsia (ABE) comemorou a "Semana de Conscientização sobre a Importância do Ácido Fólico" atuando em ambulatórios de Ginecologia, Epilepsia e na Casa da Mulher. Esta campanha consistiu em levar informações às mulheres sobre a importância em manter níveis adequados desta vitamina no organismo, especialmente nas que tomam drogas antiepilépticas, em gestantes e naquelas planejando engravidar. Na ocasião foi aplicado um breve questionário a respeito da informação que tinham sobre esta necessidade. Foi distribuída uma cartilha com informações sobre a importância do ácido fólico e pulseiras comemorativas representativas da campanha. Em paralelo foi realizada pesquisa para verificar o cumprimento da Lei Federal de 13 de dezembro de 2002 que obrigou a fortificação com ferro e ácido fólico em farinhas de trigo e de milho e seus derivados. Unitermos: Semana de Conscientização sobre a Importância do Ácido Fólico; deficiência de ácido fólico; vitamina B9. ABSTRACT Week of Awareness About the Importance of Folic AcidIn the first week of October, the Associação Brasileira de Epilepsia (ABE) celebrated the Week of Awareness of the importance of folic acid. On this occasion, representatives of the ABE were present in Women's Outpatient Clinics such as Gynecology, Epilepsy Clinic and that of the Woman's Home giving information to women about the importance of maintaining adequate levels of this vitamin in the organism. It was especially emphasized for those who were taking antiepileptic drugs as well as those who were pregnant or planning pregnancy. At that time, a brief questionnaire was applied regarding the information they had about this necessity. A booklet containing information regarding the importance of folic acid and wristbands as tokens of the commemoration were distributed. Besides this, a survey was done related to the observation of the Federal Law of December 13, 2002, which enforced the strengthening of wheat and corn flour and their derivatives with iron and folic acid.

Efeito da fortificação alimentar com ácido fólico na prevalência de defeitos do tubo neural

“…The NTD prevalences found in the city of Recife, 0.72 and 0.51:1,000 LB, in the pre-and post-fortifi cation periods respectively, were lower than the rates found in previous surveys in Brazil, which varied between 0.83:1,000 and 1.87:1,000 LB, 10,15 and in Latin American countries, where prevalences of 1.5:1,000 LB 10 were observed. NTD prevalence varies according to period in time and area; it is very low in Finland (0.4/1,000 LB), high in Mexico (3.3/1,000) and very high in southern Wales (up to 12.5/1,000).…”

“…3,19 Even though prevalence of these congenital defects varies according to the period in time and area, it is usually 1/1,000 live births, 1 with anencephaly and spina bifi da cases predominating. 1,9,11 In Brazil, this rate is estimated to vary around 1.6/1,000 live births, 15 even though publications on this problem are still scarce. 19 Etiology of neural tube defects has not been clarifi ed yet, with multifactorial inheritance resulting from the interaction between genetic and environmental factors being considered.…”

Avaliação da metodologia microbiológica para determinação de 5-metiltetrahidrofolato em suco de caju (Anacardium occidentale L.)

“…maçã, morango, mamão, laranja e caju. Folatos em alimentos são encontrados principalmente nas formas de 5-metiltetrahidrofolato (5-MTHF) e formiltetrahidrofolato (formil-THF), sendo o 5-MTHF a forma mais abundante em produtos de origem vegetal (BARRIOS; GÓMEZ, 1997;NOGUEIRA;COZZOLINO, 1998;MAYES, 1999;FOOD...;WORLD..., 2000;NASSER et al, 2005;SANCHO, 2006;QUINATO;DEGÁSPARI;VILELA, 2007;TÂMEGA;COSTA, 2007;TAM et al, 2009). …”

Development and validation of a method for the determination of folic acid in different pharmaceutical formulations using derivative spectrophotometry

“…Folic acid (FA) and folates, which are different chemical forms of vitamin B 9 , belong to the water-soluble B-group vitamins (Zare, Shishehbore, Nematollahi, 2011;Catharino, Godoy, Lima-Pallone, 2006;Nasser et al, 2005). Folate is a generic term for compounds possessing vitamin activity similar to that of pteroylglutamic acid, and is the form of the vitamin naturally present in foods (Krishnaswamy, Nair, 2001).…”

“…Folic acid is a synthetic form of folate, found in vitamin supplements and fortified foods (Bailey, 2000). The main dietary sources of folic acid are spinach, white beans, asparagus, dark-leaved vegetables, Brussels sprouts, soybean and its derivatives, oranges, and melons, amongst others (Nasser et al, 2005;Deconinck et al, 2011). An important feature of vitamins is that they are generally not synthesized by mammalian cells and must therefore be supplied in sufficient amounts in the diet (Aurora-Prado et al, 2004).…”