Sensitive dual-labeled electrochemical aptasensor for simultaneous detection of multi-antibiotics in milk

Li, Falan; Wu, Yanfang; Chen, Dongfei; Guo, Yemin; Wang, Xiangyou; Sun, Xia

doi:10.1016/j.ijhydene.2021.04.007

Cited by 21 publications

(14 citation statements)

References 34 publications

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“…The presence of KAN and STR disrupted the hybridization, leading to changes in the peaks associated with the content of Cd 2+ and Pb 2+ . Subsequently [ 56 ], another bioplatform was presented for the multiplex analysis of KAN and tobramycin (TOB), using biotinylated RNA aptamer strands responsible for specific recognition of the antibiotics. Due to the high affinity between streptavidin, previously modified with QDs (CdS or PbS), and biotin, both were conjugated, and the resulting aptameric system immobilized on the surface of a gold electrode modified with gold nanoshells.…”

Section: Electrochemical Devices/platformsmentioning

confidence: 99%

Progress and Challenge of Sensors for Dairy Food Safety Monitoring

Fernández González,

Badía Laíño,

Costa-Fernández

et al. 2024

Sensors

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One of the most consumed foods is milk and milk products, and guaranteeing the suitability of these products is one of the major concerns in our society. This has led to the development of numerous sensors to enhance quality controls in the food chain. However, this is not a simple task, because it is necessary to establish the parameters to be analyzed and often, not only one compound is responsible for food contamination or degradation. To attempt to address this problem, a multiplex analysis together with a non-directed (e.g., general parameters such as pH) analysis are the most relevant alternatives to identifying the safety of dairy food. In recent years, the use of new technologies in the development of devices/platforms with optical or electrochemical signals has accelerated and intensified the pursuit of systems that provide a simple, rapid, cost-effective, and/or multiparametric response to the presence of contaminants, markers of various diseases, and/or indicators of safety levels. However, achieving the simultaneous determination of two or more analytes in situ, in a single measurement, and in real time, using only one working ‘real sensor’, remains one of the most daunting challenges, primarily due to the complexity of the sample matrix. To address these requirements, different approaches have been explored. The state of the art on food safety sensors will be summarized in this review including optical, electrochemical, and other sensor-based detection methods such as magnetoelastic or mass-based sensors.

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Section: Electrochemical Devices/platformsmentioning

confidence: 99%

Progress and Challenge of Sensors for Dairy Food Safety Monitoring

Fernández González,

Badía Laíño,

Costa-Fernández

et al. 2024

Sensors

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“…The aforementioned examples can be further extended if considering other types of electrodes, such as: screen-printed carbon electrodes coated with carbon-black NPs-AuNPs composites to detect Cd(II) ions in water [ 40 ] or coated with exonuclease-assisted AuNPs-MOFs for detection of streptomycin in food [ 41 ]; fluorine-doped tin oxide electrodes coated with BiVO 4 -2D-C 3 N 4 photoanode with II type heterojunction to detect microcystin-LR in water [ 42 ]; Au electrodes coated with highly-porous Au nanostructures for detection of acetamiprid in food [ 43 ]; indium tin oxide electrodes coated with core-shell LaFeO 3 -g-C 3 N 4 heterostructures for detection of streptomycin in food [ 44 ]; Au microelectrodes coated with GQDs-AuNPs composites for detection of vitamin D in serum [ 45 ]; screen-printed graphite electrodes coated with poly-3-amino-1,2,4-triazole-5-thiol-GO-AuNPs composites for detection of lipocalin-2 in serum [ 46 ]; indium tin oxide electrodes coated with TiO 2 -BiOI-BiOBr visible-light photosensitive material to detect streptomycin in food and serum [ 47 ]; screen-printed carbon electrodes coated with magnetic GO-Fe 3 O 4 to detect organophosphorus pesticides in food [ 48 ]; Pt electrodes coated with AgNPs and reacted with luminol-hydrogen peroxide to detect kanamycin in food [ 49 ]; Au electrodes coated with polyethyleneimine-functionalized reduced GO-AuNCs for detection of chloramphenicol in food [ 50 ]; Au electrodes coated with polyethyleneimine-graphite-like carbon nitride/Au nanowires (AuNWs) for detection of chloramphenicol in food [ 51 ]; Au electrodes coated with Au nanospheres (AuNSs) and functionalized with CdSQDs and PdSQDs for detection of kanamycin and tobramycin in serum [ 52 ]; and exonuclease-assisted Au electrodes coated with DNA nanostructures and horseradish peroxidase-functionalized AuNPs for detection of kanamycin in food [ 53 ].…”

Section: Biosensors Based On Hybrid Biomolecules-nanomaterials Compos...mentioning

confidence: 99%

Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications

Fata

Gabriele²,

Angelucci³

et al. 2023

Sensors

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The demonstration of the first enzyme-based electrode to detect glucose, published in 1967 by S. J. Updike and G. P. Hicks, kicked off huge efforts in building sensors where biomolecules are exploited as native or modified to achieve new or improved sensing performances. In this growing area, bionanotechnology has become prominent in demonstrating how nanomaterials can be tailored into responsive nanostructures using biomolecules and integrated into sensors to detect different analytes, e.g., biomarkers, antibiotics, toxins and organic compounds as well as whole cells and microorganisms with very high sensitivity. Accounting for the natural affinity between biomolecules and almost every type of nanomaterials and taking advantage of well-known crosslinking strategies to stabilize the resulting hybrid nanostructures, biosensors with broad applications and with unprecedented low detection limits have been realized. This review depicts a comprehensive collection of the most recent biochemical and biophysical strategies for building hybrid devices based on bioconjugated nanomaterials and their applications in label-free detection for diagnostics, food and environmental analysis.

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“…The Apt is immobilized on MBs by strong binding of biotin (bio) on Apt and streptavidin (SA) encapsulated in MBs. 24 Then the double strain is formed with Apt by the base complementary pairing of cDNA. Without Pb 2+ , the MBs@Apt/cDNA system is not altered and the electrochemical biosensor is not triggered.…”

Section: Principle Of Electrochemical Biosensor For Pb 2+ Detectionmentioning

confidence: 99%