Sensitivity Evaluation of Clinical Strains of C. Albicans Isolated From Patients With Pharyngomycosis to the Combined Effect of Monarda Essential Oil and Antifungal Drugs

Zachepylo, Svitlana V.

doi:10.29254/2077-4214-2021-1-159-184-188

Cited by 1 publication

(2 citation statements)

References 7 publications

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“…These patients have a large medical burden of antibiotics, corticosteroids, immunostimulants, cytostatins, etc., which cause the development of candidiasis in the oral cavity [5,6]. In this respect, antimycotics prescription is an additional burden.…”

Section: Results Of the Research And Their Discussionmentioning

confidence: 99%

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Influence of Medicinal Plants Extracts from the Flora of Ukraine on the Growth of Cultures of Candida Yeast Fungi Selected from Dental Patients

Ohiienko

2023

Arch. clin. med.

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Antimycotics, which are widely used in this case, increasingly do not give the desired effect, since various types of Candida fungi are constantly modified forming resistant strains. This necessitates the search for new antifungal medication to affect them. From this point of view, medicinal plants are interesting for the research. They contain a number of biologically active compounds including substances that have antifungal properties against yeast-like fungi. The aim. The objective of our research was to study in an experiment the influence of medicinal plants extracts of the flora of Ukraine on the growth of cultures of Candida various species associated with dental pathology. Materials and methods. We selected 15 aqueous-ethanol extracts for further research which showed significant antifungal activity against C. albicans, C. tropicalis, C.lusitaniae, C.kefyr і C. lipolytica.on the basis of the initial screening of the antifungal properties of various medicinal plants of the flora of Ukraine. Results. According to the results of the work performed, 15 extracts were selected for further study by a more accurate method of serial dilutions in order to establish their fungicidal/fungistatic concentrations. The results of the testing showed that all 16 studied extracts in the dilution range from 1:20 to 1:640 showed at least a fungistatic effect against most strains of Candida fungi associated with dental pathological processes. Conclusions. The obtained research results indicate a significant prospect of using plant extracts and medication based on them for oral thrush treatment.

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Section: Results Of the Research And Their Discussionmentioning

confidence: 99%

“…In this respect, antimycotics prescription is an additional burden. Medication made from the studied plant extracts can be an alternative [7,5,6,8].…”

Section: Results Of the Research And Their Discussionmentioning

confidence: 99%

Influence of Medicinal Plants Extracts from the Flora of Ukraine on the Growth of Cultures of Candida Yeast Fungi Selected from Dental Patients

Ohiienko

2023

Arch. clin. med.

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show abstract

Sensitivity Evaluation of Clinical Strains of C. Albicans Isolated From Patients With Pharyngomycosis to the Combined Effect of Monarda Essential Oil and Antifungal Drugs

Cited by 1 publication

References 7 publications

Influence of Medicinal Plants Extracts from the Flora of Ukraine on the Growth of Cultures of Candida Yeast Fungi Selected from Dental Patients

Influence of Medicinal Plants Extracts from the Flora of Ukraine on the Growth of Cultures of Candida Yeast Fungi Selected from Dental Patients

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