Sensor arrays for liquid sensing – electronic tongue systems

Ciosek, Patrycja; Wróblewski, Wojciech

doi:10.1039/b705107g

Cited by 372 publications

(230 citation statements)

References 254 publications

(488 reference statements)

Supporting

Mentioning

225

Contrasting

Unclassified

Order By: Relevance

“…The ETongue approach has shown a very good correlation with the human taste panel study (40)(41)(42). It equips a probe which consists of artificial multichannel taste sensors (ZZ, AB, BA, BB, CA, DA, and JE) for converting taste responses to electric signals (43). The signal of each sensor after each assay was integrated into a matrix of data that was computed by multidimensional statistic tools.…”

Section: Taste Assessment Using An Electronic Tonguementioning

confidence: 99%

Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures

et al. 2014

View full text Add to dashboard Cite

Abstract. Several attempts have been made to mask the bitter taste of oral formulations, but none have been made for injectable formulations. This study aims to mask the bitter taste of dental lidocaine HCl (LID) injection using hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium saccharin. Inclusion complexes of LID and HP-β-CD were prepared by the solution method in 1:1 and 1:2 M ratios. Inclusion complexes in solution were studied using phase solubility in phosphate buffer solutions (pH 8, 9, and 10). Freeze-dried inclusion complexes were characterized using differential scanning calorimetry (DSC), Xray, Fourier transform infrared (FT-IR), nuclear magnetic resonance (NMR), scanning electron microscopy (SEM), and in vitro release. Injectable formulations were prepared using inclusion complexes and characterized for stability and for taste using an Alpha MOS ASTREE electronic tongue (ETongue). The association constants of HP-β-CD with lidocaine-free base and its ionized form were found to be 26.23± 0.00025 and 0.8694±0.00045 M −1 , respectively. Characterization studies confirmed the formation of stable inclusion complexes of LID and HP-β-CD. Injectable formulations were found to be stable for up to 6 months at 4°C, 25°C, and 40°C. The taste evaluation study indicated that HP-β-CD (1:1 and 1:2 M ratios) significantly improved the bitter taste of LID injectable formulation. In conclusion, inclusion complex in the 1:1 M ratio with 0.09% sodium saccharin was considered to be optimum in masking the bitter taste of LID.

show abstract

Section: Taste Assessment Using An Electronic Tonguementioning

confidence: 99%

Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Presently, chemical sensors are mainly fabricated based on metal-oxide semiconductors, quartz crystal microbalances, surface plasmon resonators, or surface acoustic wave devices (1)(2)(3)(4)(5). These sensors were developed with the aim of achieving good portability while demonstrating high sensitivity and selectivity, in order that they find application as mobile chemical sensors in the monitoring of environmental or physical conditions (6). However, it has been difficult to develop an adequate chemical sensor that combines all of these properties.…”

mentioning

confidence: 99%

Highly sensitive and selective odorant sensor using living cells expressing insect olfactory receptors

Misawa

Mitsuno

Kanzaki

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

113

View full text Add to dashboard Cite

This paper describes a highly sensitive and selective chemical sensor using living cells (Xenopus laevis oocytes) within a portable fluidic device. We constructed an odorant sensor whose sensitivity is a few parts per billion in solution and can simultaneously distinguish different types of chemicals that have only a slight difference in double bond isomerism or functional group such as ─OH, ─CHO and ─Cð═OÞ─. We developed a semiautomatic method to install cells to the fluidic device and achieved stable and reproducible odorant sensing. In addition, we found that the sensor worked for multiple-target chemicals and can be integrated with a robotic system without any noise reduction systems. Our developed sensor is compact and easy to replace in the system. We believe that the sensor can potentially be incorporated into a portable system for monitoring environmental and physical conditions. fluidic channel | odorant receptor | robot | Xenopus oocyte

show abstract

“…Among the many systems employing multivariate data analysis, particularly relevant for biosensing are those related to electronic tongues and noses [38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56]. The latter comprise arrays of chemical sensors, whose response constitutes a taste or odor pattern, respectively.…”

Section: Electronic Tongues and Nosesmentioning

confidence: 99%

Information Visualization to Enhance Sensitivity and Selectivity in Biosensing

Oliveira¹,

Pavinatto²,

Constantino³

et al. 2012

Biointerphases

View full text Add to dashboard Cite

An overview is provided of the various methods for analyzing biosensing data, with emphasis on information visualization approaches such as multidimensional projection techniques. Emphasis is placed on the importance of data analysis methods, with a description of traditional techniques, including the advantages and limitations of linear and non-linear methods to generate layouts that emphasize similarity/dissimilarity relationships among data instances. Particularly important are recent methods that allow processing high-dimensional data, thus taking full advantage of the capabilities of modern equipment. In this area, now referred to as e-science, the choice of appropriate data analysis methods is crucial to enhance the sensitivity and selectivity of sensors and biosensors. Two types of systems deserving attention in this context are electronic noses and electronic tongues, which are made of sensor arrays whose electrical or electrochemical responses are combined to provide “finger print” information for aromas and tastes. Examples will also be given of unprecedented detection of tropical diseases, made possible with the use of multidimensional projection techniques. Furthermore, ways of using these techniques along with other information visualization methods to optimize biosensors will be discussed.

show abstract

Sensor arrays for liquid sensing – electronic tongue systems

Cited by 372 publications

References 254 publications

Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures

Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures

Highly sensitive and selective odorant sensor using living cells expressing insect olfactory receptors

Information Visualization to Enhance Sensitivity and Selectivity in Biosensing

Contact Info

Product

Resources

About