Sentinel Lymph Node Biopsy for Eyelid and Conjunctival Tumors

Pfeiffer, Margaret L.; Savar, Aaron; Esmaeli, Bita

doi:10.1097/iop.0b013e31827472c5

Cited by 69 publications

(60 citation statements)

References 49 publications

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“…17 Others have also supported this recommendation. 33 There are no studies that evaluate the role of elective or prophylactic lymph node dissection in extraocular SC.…”

Section: Nodal Managementmentioning

confidence: 99%

Management Considerations in Extraocular Sebaceous Carcinoma

Chang

Miller

Elenitsas

et al. 2016

Dermatologic Surgery

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“…17 Others have also supported this recommendation. 33 There are no studies that evaluate the role of elective or prophylactic lymph node dissection in extraocular SC.…”

Section: Nodal Managementmentioning

confidence: 99%

Management Considerations in Extraocular Sebaceous Carcinoma

Chang

Miller

Elenitsas

et al. 2016

Dermatologic Surgery

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“…Although SLNB recommendations exist for conjunctival melanoma and cutaneous melanoma, as well as sebaceous cell carcinoma and Merkel cell carcinoma, the indications for SLNB for conjunctival SCC remain unclear. 29 Ideally, SLNB should provide prognostic criteria based on more accurate tumor staging and thus allow more tailored therapeutic options. Presently, only one study in the literature performed SLNBs in a small series of 6 patients with conjunctival SCC and thus its utility remains to be seen.…”

Section: Discussionmentioning

confidence: 99%

Local and Regional Spread of Primary Conjunctival Squamous Cell Carcinoma

Desai¹,

Pruzan

Geske

et al. 2018

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Two cases of biopsy-proven conjunctival squamous cell carcinoma (SCC) that developed local and regional spread are described. The cases involved a 65-year-old woman and a 79-year-old man who were initially treated at outside institutions for SCC of the conjunctiva. The patients did not have a history of immune compromise. The female patient presented with direct extension into the lacrimal gland but deferred recommended exenteration. Despite eventual exenteration, she developed metastasis to a neck node 6 months later, which was treated with radiotherapy. The male patient presented with local recurrence and a parotid node metastasis treated with exenteration, parotidectomy, selective neck dissection, and postoperative radiotherapy. Review of the outside pathology of both cases revealed positive tumor margins at the time of original resection. Local control of conjunctival SCC is of critical importance to reduce the risk of orbital extension and regional spread.

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“…of sentinel lymph node biopsies [106,107]. A significant relation between tumor-associated lymphangiogenesis and mortality, local recurrence and metastasis has also been shown for conjunctival melanoma [27].…”

Section: Ocular Malignancies and Their Association To Lymphatic Vesselsmentioning

confidence: 94%