Sentinel node biopsy for high-risk cutaneous squamous cell carcinoma

Parotid Sentinel Lymph Node Biopsy Combined With Intraoperative Facial Nerve Monitoring In Head and Neck Tumor

“…It provides information specific to the individual patient and so is important to provide appropriate personalized and optimal treatment regimes to eliminate the cancer [6,[8][9][10][11][12]. Morton [10] confirmed with the long-term results of the Multicenter Selective Lymphadenectomy Trial that SNB in head and neck melanoma increases both the disease-free and the specific survival of the patient.…”

High-risk cutaneous squamous cell carcinoma and the emerging role of sentinel lymph node biopsy: A literature review

“…A review of all case series reporting SLNB in cSCC is detailed in Table IV. 13,18,28,[41][42][43][44][45][46][47][48][49][50][51][52] Our systematic review identified an overall positive rate for SLNB of 13.9% (32 of 231 patients) and a false-negative rate of 4.6% (10 of 215 patients) in cSCC. The authors usually stated that patients had high-risk factors for lymph node involvement.…”

“…Takahashi et al 46 46 To our knowledge, this is the only study evaluating long-term outcomes and suggests a prognostic role of SLNB for predicting survival. In a case series, 17 patients underwent SLNB and had 2 or more years follow-up; 6 (35.2%) Edition only recognizes these 4 high-risk features in addition to location on the ear or lip.…”

“…Larger series and longer follow-up are needed to demonstrate an improvement in survival documented in only 1 study. 46 …”

Sentinel lymph node biopsy for cutaneous head and neck malignancies

“…A small study out of Japan followed 26 people undergoing SLNB. The 3-year survival rate was 100% for negative SLN and 21% for positive SLN [81]. Two additional small case series report no recurrence or disease-specific death in the negative SLN patients during the study of follow-up time [82,83].…”