Sepsis and septic shock in emergency departments of Mexico: a multicenter point prevalence study

Abstract

Introduction: Sepsis is one of the main reasons for consultation at emergency departments. Objective: To identify the prevalence of sepsis in emergency departments of Mexico. Method: Cross-sectional study with a 30-day follow-up of patients diagnosed with sepsis or septic shock; demographic variables, management and outcomes were analyzed. Results: In 68 emergency departments analyzed, 2379 patients were attended to, out of whom 307 had sepsis. The prevalence of sepsis was 12.9 %, and overall mortality was 16.93 %, which in the cases of sepsis was 9.39 %, and in those of septic shock, 65.85 %; no significant differences were identified in demographic variables or type of hospital. A significantly higher fluid balance was observed within the first three hours in those patients who died, as well as a lack of adherence to international resuscitation recommendations. Conclusions: A high prevalence of sepsis was found in Mexican emergency departments. Mortality of patients with septic shock was similar and even higher than that internationally reported.

Acute Myocardial Injury Assessed by High-Sensitivity Cardiac Troponin I Levels in Adult Patients with Early Sepsis at a Tertiary Referral Center in Mexico: An Exploratory Study

“…A descriptive study from Mexico included 68 emergency medical services, where 2379 patients were treated. The prevalence of sepsis was 12.9% with an overall mortality of 16.93%, which in cases of sepsis was 9.39% and in cases of septic shock was 65.85% (the latter with a mortality higher than that reported internationally) [14]. Also, in a recent study of the Mexican population, it was found that of 65 patients analyzed who presented with septic shock and who were admitted to intensive care, 46% had a high serum cTnI in the first 24 h, with his being a poor predictor of mortality in these patients [15].…”

Randomized Clinical Trial of Antioxidant Therapy Patients with Septic Shock and Organ Dysfunction in the ICU: SOFA Score Reduction by Improvement of the Enzymatic and Non-Enzymatic Antioxidant System

“…In a separate evaluation, 9.3% of deaths were due to sepsis and 65.85% to septic shock. Therefore, the authors concluded there is an association between the presence of septic shock and mortality [3].…”

Septic shock of abdominal urinary focus after renal surgery [Version 1; Peer Review - In process]

“…(2) La sepsis es la manera en la que nuestro cuerpo puede llegar a responder a una infección debido a un desorden fisiológico y químico que ocurre produciendo una alteración orgánica y suele tener consecuencias muy graves que incluso pueden llevar a la muerte si no se trata de una manera adecuada, esta infección puede llegar a producir una desfavorable reacción en cadena provocando de esa manera sepsis. (3,4) Existen muchos factores de riesgo que pueden aumentar la probabilidad de contraer sepsis tales como ser persona mayor, haberse realizado cirugías complejas recientemente, personas con sistema inmune debilitado y sobre todo en personas que padezcan enfermedades crónicas como diabetes mellitus, cáncer, patologías renales, entre otras. Por otro lado, los síntomas más frecuentas causados por la sepsis se encuentra el aumento en la presión respiratoria, aumento en la frecuencia cardiaca, disnea, confusión, alza térmica y diaforesis.…”