Sequential and Amino Acid Residue Compositions of Adrenocorticotropic Hormone Preparations of Various Levels of Activity¹

Ionic Inhibition of Bacterial Growth. II. Relationship of Ionic Inhibition to DNA-Protein Biosynthesis1

“…already present in the medium. 6 Turbidometer readings: % transmission ; no growth «= 100%. transmission; maximal growth = 10% transmission; "half maximal" growth = 55% transmission.…”

“…Substituting for log [Ea] in (6) log K = log [EaBidlog [Bu,] -ß' + ,µ (10) where the new constant ß1 = ß + log a. Furthermore, if EaBi2 is the growth limiting enzyme, then the growth rate, f, is proportional to the concentration of EaBi2…”

Application of a Quantitative Method of Peptide Analysis to the N-Terminal Sequence of Lysozyme1

“…Lack of difficulty with reactive sidechains and applicability of this general type of method to quantitative studies of structure and biological metamorphosis are thus again indicated.7 Discernible advantages and disadvantages of subtractive methodology of this type have been discussed. 7 In addition to the points previously summarized,7 it should be repeated that the present kind of method permits configurational designations. The L-isomer may be determined directly as indicated; D-residues may be identified by comparison of microbiological and chromatographic results.…”

The Pituitary and Adrenals

“…The isolation and properties of alpha-corticotrophin have been described (162). The most active ACTH preparations lack isoleucine and threonine (164). The most active ACTH preparations lack isoleucine and threonine (164).…”