This article details an innovative undergraduate veterinary nursing online educational module integrating workplace safety, management, and communication concepts with a review of hazards for immunocompromised individuals, such as zoonoses, and veterinary workplace risks to reproductive health. This flipped-classroom online session was designed based on the interactive, constructive, active, passive (ICAP) framework for active learning and using the principles of self-determination theory applied to the educational setting. The session used the expertise of a veterinary nursing instructor and a physician. The compressed time frame of veterinary nursing education compels veterinary nursing instructors to incorporate actionable real-world workplace issues and strategies into foundational science content in the classroom. The published literature on veterinary nursing education offers limited examples of this type of integration. This article breaks new ground in offering an example of an educational innovation in a veterinary nursing curriculum, building learner knowledge and skills in an interactive session.