Serological evidence of Hantaan-related viruses in Hong Kong

Shortridge, K. F.; Lee, H.W.; Duc, James W. Le; Wong, Tze Wai; Chau, G.W.; Rosen, Léon

doi:10.1016/0035-9203(87)90148-9

Cited by 7 publications

(5 citation statements)

References 7 publications

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“…In 1985, four SEOV isolations were made from urban rats in Hong Kong (strains R 85/14, 19, 35, and 40) [39]. Rat-associated hantavirus infection in both rat and human sera in Hong Kong was subsequently confirmed by IFA and PRNT [40], and two HFRS cases were serologically confirmed ([26], pp. 804 and 807).…”

Section: Overview Of Chronological Seov Findings By Continentmentioning

confidence: 99%

Wild Rats, Laboratory Rats, Pet Rats: Global Seoul Hantavirus Disease Revisited

Clément¹,

LeDuc

Lloyd

et al. 2019

Viruses

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Recent reports from Europe and the USA described Seoul orthohantavirus infection in pet rats and their breeders/owners, suggesting the potential emergence of a “new” public health problem. Wild and laboratory rat-induced Seoul infections have, however, been described since the early eighties, due to the omnipresence of the rodent reservoir, the brown rat Rattus norvegicus. Recent studies showed no fundamental differences between the pathogenicity and phylogeny of pet rat-induced Seoul orthohantaviruses and their formerly described wild or laboratory rat counterparts. The paucity of diagnosed Seoul virus-induced disease in the West is in striking contrast to the thousands of cases recorded since the 1980s in the Far East, particularly in China. This review of four continents (Asia, Europe, America, and Africa) puts this “emerging infection” into a historical perspective, concluding there is an urgent need for greater medical awareness of Seoul virus-induced human pathology in many parts of the world. Given the mostly milder and atypical clinical presentation, sometimes even with preserved normal kidney function, the importance of simple but repeated urine examination is stressed, since initial but transient proteinuria and microhematuria are rarely lacking.

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Section: Overview Of Chronological Seov Findings By Continentmentioning

confidence: 99%

Wild Rats, Laboratory Rats, Pet Rats: Global Seoul Hantavirus Disease Revisited

Clément¹,

LeDuc

Lloyd

et al. 2019

Viruses

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“…Clinical cases of HFRS have also been reported in other countries and districts in Asia [31][32][33][34][35][36] (Table 1). Serological investigation indicated that there were strong evidences of hantaviral infections in humans in Israeli, Kuwait, Laos, Malaysia, Philippines, Viet Nam and the China Hong Kong Special Administrative Region [37][38][39][40][41][42]. Hantaviral infection was also demonstrated in rodents in Cambodia, though there has been no report of human infections [43] (Table 1).…”

Section: Asiamentioning

confidence: 99%

Hantavirus Infection: a review and global update

Formenty

Roth

2008

J Infect Dev Ctries

202

215

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Hantaviruses have the potential to cause two different types of diseases in human: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS, initially described clinically at the turn of the 20 th century, occurs endemically in the Asian and European continents, while HPS, recognized as a clinical entity since 1993, represents the prototype of emerging diseases occurring in the Western hemisphere. Approximately 150,000 to 200,000 cases of HFRS are hospitalized each year world wide, with most of the cases occurring in the developing countries. The case fatality rate of HFRS varies from <1% to 12% depending on the viruses. Although HPS is much smaller in number than HFRS, with approximately 200 HPS cases per year in the Americas, the average case fatality rate is 40%. The reported cases of hantaviral infection is increasing in many countries and new hantavirus strains have been increasingly identified worldwide, which constitutes a public health problem of increasing global concern. Hantaviral infection might be underestimated due to its asymptomatic and nonspecific mild infection, and the lack of simple standardized laboratory diagnostics in hospitals, especially in the developing countries. This review summarizes the current knowledge on virology, epidemiology, clinical manifestation, laboratory diagnostics, treatment and prevention of hantaviruses and hantaviral infections.

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“…[34][35][36] In surveys of studies from regions where the HTN and SEO viruses, but not PUU virus, occur endemically, antibodies to hantavirus has been reported in samples from small and mediumsized wild mammals such as moles, weasels, hares, foxes, roes, and also among domestic animals such as cats, dogs, and pigs. [37][38][39][40][41][42] Furthermore, in an outbreak of HFRS among laboratory staff, IFA reactions of low titer towards HTN virus were found in rabbits, guinea pigs, dogs, and cats. 43 In line with those studies on the HTN/SEO virus group, [37][38][39][40][41][42][43] the present data may reflect a more general susceptibility to hantavirus infection among mammals.…”

Section: Discussionmentioning

confidence: 99%

“…[37][38][39][40][41][42] Furthermore, in an outbreak of HFRS among laboratory staff, IFA reactions of low titer towards HTN virus were found in rabbits, guinea pigs, dogs, and cats. 43 In line with those studies on the HTN/SEO virus group, [37][38][39][40][41][42][43] the present data may reflect a more general susceptibility to hantavirus infection among mammals. Obviously, such susceptibility does not necessarily imply that the infection rate should be high.…”

Section: Discussionmentioning

confidence: 99%

Serologic evidence of Puumala virus infection in wild moose in northern Sweden.

Ahlm¹,

Wallin²,

Lundkvist³

et al. 2000

The American Journal of Tropical Medicine and Hygiene

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Abstract. Puumala (PUU) virus is the causative agent of nephropathia epidemica, the Scandinavian form of hemorrhagic fever with renal syndrome. The infection is acquired by airborne transmission of PUU virus from its rodent reservoir, the bank vole. Besides serologic data indicating that the virus may spread also to heterologous rodents, there is little information on the susceptibility of wild living animals to PUU virus. We studied the occurrence of antibodies to PUU virus in serum samples from 427 wild-living moose, of which 260 originated from the PUU virus-endemic northern and central parts of Sweden and 167 originated from the southern, nonendemic part of Sweden. Samples from 5 animals showed reactivity in an ELISA for recombinant PUU virus nucleocapsid protein, an immunofluorescent assay, and a neutralization test. These 5 animals all originated from the PUU virus-endemic northern part of Sweden. In conclusion, 5 of 260 moose from the endemic region showed convincing serologic evidence of past PUU virus infection. The seroprevalence was low, suggesting that the moose is subjected to endstage infection rather than being part of an enzootic transmission cycle.

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Serological evidence of Hantaan-related viruses in Hong Kong

Cited by 7 publications

References 7 publications

Wild Rats, Laboratory Rats, Pet Rats: Global Seoul Hantavirus Disease Revisited

Wild Rats, Laboratory Rats, Pet Rats: Global Seoul Hantavirus Disease Revisited

Hantavirus Infection: a review and global update

Serologic evidence of Puumala virus infection in wild moose in northern Sweden.

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