Serotonin involvement in the electroacupuncture- and moxibustion-induced gastric emptying in rats

Sugai, Gisele C.M.; Freire, Anaflávia de Oliveira; Tabosa, Angela; Yamamura, Ysao; Tufik, Sérgio; Mello, Luiz E.

doi:10.1016/j.physbeh.2004.07.003

Cited by 28 publications

(15 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The general theory of TCM is based on the premise that there are patterns of energy flow (Qi) through the body that are essential for health, and disruptions of this flow are believed to be responsible for disease [13] . Medical treatments based on TCM often rely on a combination of needle insertion (acupuncture) and thermal stimulation (moxibustion) to achieve optimal results [14] .…”

mentioning

confidence: 99%

“…Acupuncture consists of stimulation of anatomical locations on the skin by thin, solid, metallic needles, which are manipulated manually or with the help of an electrical device. Stimulation of these areas by heat is called moxibustion (MO), a technique that applies heat to acupoints by burning a compressed, powdered, combustible mass obtained from the ground young leaves of an Eurasian artemisia (Artemisia vulgaris) [13][14][15] .…”

mentioning

confidence: 99%

See 1 more Smart Citation

Electroacupuncture and Moxibustion Attenuate the Progression of Renal Disease in 5/6 Nephrectomized Rats

Paterno

Freire

Soares³

et al. 2008

Kidney Blood Press Res

View full text Add to dashboard Cite

Background/Aim: Chronic kidney disease is a worldwide public health problem and the prevention of its progression is still a major challenge in nephrology. Specific therapies that inhibit or attenuate this process are neither available nor satisfactory. Traditional Chinese medicine has been increasingly recognized as an effective therapeutic approach in several fields of medicine. The aim of this study was to investigate the effects of electroacupuncture (EA) and moxibustion (MO) in an experimental model of progressive renal disease in rats. Methods: Twenty-one male Wistar rats were submitted to 5/6th nephrectomy (NX) and assessed 8 weeks later and were divided into three groups: NX = only 5/6 NX, NX-AS = 5/6 NX and a 20-min EA-MO session in sham points, and NX-AM = 5/6 NX and a 20-min EA-MO session in three real acupuncture points. The treatment consisted of 16 sessions twice a week. Renal function, urine volume, serum creatinine, 24-hour proteinuria, direct and indirect blood pressure, glomerulosclerosis and tubulointerstitial fibrosis indices were assessed. Results: The NX-AM group showed a significant decrease in all investigated parameters when compared to the control groups. Conclusion: Our results suggest that EA and MO attenuated the progression of renal disease in the experimental model of 5/6 NX.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Electroacupuncture and Moxibustion Attenuate the Progression of Renal Disease in 5/6 Nephrectomized Rats

Paterno

Freire

Soares³

et al. 2008

Kidney Blood Press Res

View full text Add to dashboard Cite

show abstract

“…14 Other mechanisms reported in the literature include enhancement of blood flow, 25 activation of A delta and/or C afferent fiber, 26 and involvement of the serotonin pathway. 27 …”

Section: Electroacupuncture and Gastric Emptyingmentioning

confidence: 99%

Complementary and Alternative Medicine for Gastroparesis

Lee

Chen

Yin

2015

Gastroenterology Clinics of North America

View full text Add to dashboard Cite

“…Numerous studies have evaluated the concurrent use of moxibustion with other physical technologies, especially acupuncture (Anastasi and McMahon, 2003;Sugai et al, 2004;Shin et al, 2006). We have reported the change in the in vitro skin permeation efficacy of FITC-dextran with a mean molecular weight of 4 kDa induced by a single moxibustion technique (Cao et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Pretreatment effects of moxibustion on the skin permeation and skin and muscle concentrations of salicylate in rats

Cao

Tazawa

Ishii

et al. 2011

International Journal of Pharmaceutics

View full text Add to dashboard Cite

The effect of moxibustion on the in vitro and in vivo skin permeation of salicylate was evaluated in rats. First, the effect of moxibustion pretreatment on the elimination pharmacokinetics of salicylate after i.v. injection in rats was determined: no clear difference was observed in the plasma profiles of salicylate (SA) with or without moxibustion pretreatment. However, much higher skin and muscle concentrations of salicylate were observed after its i.v. injection. Next, an in vitro skin permeation study of SA was performed after moxibustion pretreatment. Moxibustion pretreatment increased the skin permeation of SA, and the extent of the increase in SA skin permeation was related to the strength of moxibustion ignition. More intense treatments produced higher skin permeation. A similar enhancement effect on the skin permeation of SA was observed in in vivo studies. Interestingly, the skin/plasma and muscle/plasma ratios of SA were markedly increased by moxibustion pretreatment. These results were due to the induction of enhanced skin permeation and lower clearance into the cutaneous vessels by moxibustion ignition. Combination treatment involving moxibustion and the topical application of drugs such as NSAID may be useful for increasing local pharmaceutical effects by enhancing the drug concentration in the skin and muscle underneath the topical application site.

show abstract

Serotonin involvement in the electroacupuncture- and moxibustion-induced gastric emptying in rats

Cited by 28 publications

References 30 publications

Electroacupuncture and Moxibustion Attenuate the Progression of Renal Disease in 5/6 Nephrectomized Rats

Electroacupuncture and Moxibustion Attenuate the Progression of Renal Disease in 5/6 Nephrectomized Rats

Complementary and Alternative Medicine for Gastroparesis

Pretreatment effects of moxibustion on the skin permeation and skin and muscle concentrations of salicylate in rats

Contact Info

Product

Resources

About