Serotype and genotype diversity of dengue viruses circulating in India: a multi-centre retrospective study involving the Virus Research Diagnostic Laboratory Network in 2018

Abstract

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Molecular Characteristic of Dengue Virus against its Outbreak response of Red Sea State, Eastern Sudan - 2020

“…Furthermore, our finding, similar to another retrospective study undertaken to investigate the circulating DENV serotypes and genotypes in India in 2018, reported that the DENV-3 was more common in Western and Northern India. DENV-3 emerged as the dominant serotype in Maharashtra in 2017, and this continued in 2018 [21]. During the current study, we did not detect DEN-1, 2 and DEN-4 in outbreak in eastern Sudan during the year 2020, the small number of samples tested from in the current study may be one of the reasons for the lack of detection of other types.…”

Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences

“…[13][14][15] Previous studies also indicated the cocirculation of DENV4 genotype I strains in Pune, along with DENV1, DENV2, and DENV3. 16,17 The current DENV vaccine effort is also thought to be hampered by antibody-dependent enhancement (ADE), whereby cross-reactive antibodies against one serotype can enhance subsequent infection by a heterologous serotype. 18 To circumvent such issues, regions or motifs of the antigen responsible for causing ADE must be eliminated from the vaccine design.…”

Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review

“…A comparison of prior approximations of entire global dengue contagions has been illustrated. Average incidences in India with maximum infected states (Karnataka, Punjab, Tamil Nadu, and Maharashtra) are shown ( Alagarasu et al, 2021 ) ( Figure 2 ). Moreover, dengue infection frequency of different Asian countries and their percentage contribution have been determined where India was found to comprise 9% of total dengue incidences, higher than Pakistan, Singapore, China, Thailand, Nepal, and Cambodia, while Vietnam and Philippines are the leading countries and recorded the highest number of dengue cases in 2021 (till May) ( Figure 3A ) ( European Centre for Disease Prevention and Control 2018 ; World Health Organization 2021b ).…”