Sertraline-Induced Acneiform Eruption

Sinha, Siddhartha; Udupa, S. L.; Bhandary, Rajeshkrishna Panambur; Praharaj, Samir Kumar; Munoli, Ravindra N

doi:10.1176/appi.neuropsych.13050113

Cited by 10 publications

(7 citation statements)

References 5 publications

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“…Some of the drugs that have been associated with this condition are oral Corticoids, Lithium (Scarfi & Arunachalam, ), Sertraline (Sinha, Udupa, Bhandary, Praharai, & Munoli, ), and some anticancer agents such as Cetuximab (Walon, Gilbeau, & Lachapelle, ), Vemurafenib or Trametinib. With respect to antipsychotic agents, Quetiapine, Haloperidol, Lamotrigine (Nielsen, Licht, & Fogh, ), or Aripiprazole (Mishra, Praharaj, Prakash, & Sinha, ) have also been associated with drug‐induced acne.…”

Section: Discussionmentioning

confidence: 99%

Oral Isotretinoin for the treatment of Aripiprazol-induced acneiform rash

Navarro‐Triviño

Ruiz

Porras-Segovia

et al. 2018

Dermatologic Therapy

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Acneiform rash is a commonly reported side effect to certain types of medications, including antipsychotic agents. Its clinical presentation consists mainly of papulopustular lesions. Other types of lesions, such as nodular or cystic, can also be observed. Body distribution of the lesions follows a similar pattern to acne vulgaris. Depending on the severity of the case, drug-induced acne may be treated in different ways. In mild cases, the use of topical antibiotics and retinoids in combination is usually effective. With more severe forms, it may be necessary to add oral antibiotics, such as tetracyclines, but a good response is not always achieved. Identification of the drug responsible for the side-effect is mandatory in refractory eruptions. Herein, we present the case of an Aripiprazole-induced acneiform rash successfully treated with oral Isotretinoin. The treatment was effective and well tolerated and there was no need to discontinue the psychopharmacological medication. This is the first study to report this modality of treatment.

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Section: Discussionmentioning

confidence: 99%

Oral Isotretinoin for the treatment of Aripiprazol-induced acneiform rash

Navarro‐Triviño

Ruiz

Porras-Segovia

et al. 2018

Dermatologic Therapy

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“…3,7 Acne was subsided following discontinuation of drug within a week, though severe lesions may take several weeks to resolve and may require topical therapy. 1,3 The use of antihistamines is important when there is associated pruritis and oral antibiotics should be used in cases of secondary infection with pustules or impetiginization. 3 In our study, acneiform eruptions associated pruritis were managed by T.Monteleukast LC…”

Section: Discussionmentioning

confidence: 99%

“…2 Eruptions are characterized by their unusual distribution, monomorphic lesions, occurrence beyond the usual age of distribution of acne vulgaris, widespread involvement and clearing of lesions when the drug is discontinued. 1,3 We report a case of prednisolone induced acneiform lesions in a 16 year old female patient.…”

Section: Introductionmentioning

confidence: 97%

“…1 It results from a direct effect on the follicular epithelium causing a focal degeneration with localized intrafollicular and perifollicular neutrophilic inflammatory reaction. 2 Eruptions are characterized by their unusual distribution, monomorphic lesions, occurrence beyond the usual age of distribution of acne vulgaris, widespread involvement and clearing of lesions when the drug is discontinued.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Case Report on Steroid Induced Acneiform Eruptions

Jeyaraj¹,

Krishnakumar²,

Sivakumar³

et al. 2017

IJOPP

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Acne is the chronic inflammatory disease of the pilosebaceous unit, characterized by the formation of comedones, erythematous papules and pustules shortly after starting topical or oral corticosteroid. We report a case of acneiform eruptions on a Eosinophilic gastroenteritis (EGE) patient who was treated with prednisolone 30 mg 1-0-0, 2 weeks, three months ago. She developed pustular rashes over the face and back on and off during past 3 months. Presently she got admitted in the gastroenterology department for reoccurence of the symptoms associated with EGE and treated with prednisolone 30 mg 1-0-0. Dermatology opinion was sought for the aggravated pustular rashes over the face and back confirmed to be prednisolone induced acneiform eruptions. Following which, prednisolone was withdrawn within 48 h of admission and treated symptomatically with Clindamycin 1% gel.

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“…ertraline is a specific serotonin reuptake inhibitor antidepressant, which is uncommonly associated with adverse cutaneous drug reactions such as rash, pruritus, dermatitis, purpura, urticaria, and rarely, Steven-Johnson syndrome. 1 There may be some unpredictable adverse drug reactions which were not reported in the literature. Here we report a patient diagnosed with depression who developed zosteriform pattern skin rash after treatment with sertraline 50 mg/day.…”

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confidence: 99%