Serum Alpha₁-Antitrypsin Mass Concentrations in a Finnish Young Male Population

Abstract

Serum a1-antitrypsin mass concentrations were estimated in 664 Finnish young males by means of single radial immunodiffusion techniques. The distribution was symmetrical with a mean of 2.70 811 and a standard deviation of 0.545 g/l. Sera containing low concentrations were re-analyzed by antigen-antibody-crossed electrophoresis. One serum contained very low levels of ai-antitrypsin and 34 moderately lowered concentrations corresponding to values seen in Pi-phenotypes ZZ and MZ, respectively. The incidence of serum at-antitrypsin deficiency seems to be similar to that found in Scandinavian populations.Scand J Clin Lab Invest Downloaded from informahealthcare.com by QUT Queensland University of Tech on 11/20/14For personal use only.