Serum analysis method combining cellulose acetate membrane purification with surface‐enhanced Raman spectroscopy for non‐invasive HBV screening

Yu, Xu; Wang, Yunyi; Lin, Huijin; Liu, Xiaokun; Zheng, Zuci; Wang, Tingyin; Feng, Shouhua

doi:10.1049/iet-nbt.2019.0274

Cited by 10 publications

(4 citation statements)

References 28 publications

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“…The analysis groups were set up as follows: (1) normoxia control pregnancy group, (2) pregnancy-induced hypertension group, and (3) treprostinil treatment group [ 14 ]. Blood samples for TNF- α and IL-6 were collected from the heart and stored at -80°C.…”

Section: Methodsmentioning

confidence: 99%

Clinical Analysis of Echocardiography and Serum IL-6 and TNF-α Changes in Pregnant Women with Hypertension

Liu

Hou

et al. 2022

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In order to explore the changes and clinical significance of serum TNF-α and IL-6 and ET levels in the pathogenesis of hypertensive disorders of pregnancy (HDIP), echocardiography, and serum IL-6 and TNF-α changes in pregnant women with a hypertensive disorder, a clinical analysis method was proposed. A retrospective analysis of 59 pregnant women who visited the obstetrics department of a provincial hospital was divided into 2 groups. The normal control group consisted of 32 normal, uncomplicated pregnant women; the preeclampsia group included 27 patients with systolic blood pressure > 140 mmHg and/or diastolic blood pressure > 90 mmHg who developed proteinuria after 20 weeks of gestation. The levels of TNF-α and IL-6 in serum of normal pregnant women and pregnant women with preeclampsia were detected by enzyme-linked immunosorbent assay (ELISA). The results showed that compared with normal pregnant women, the serum levels of TNF-α and IL-6 in the early pregnant women of Zizhi were significantly increased, and the trend of increased TNF-α and IL-6 levels was related to the severity of complications. With the mean pulmonary artery pressure > 50 mmHg , the serum TNF-α level of pregnant women was significantly higher than that of pregnant women with mean pulmonary artery pressure < 50 mmHg . The analysis found that the serum levels of TNF-α and IL-6 in patients with hypoxic gestational hypertension were significantly increased, and the results of lung tissue immunohistochemistry also showed that serum TNF-α and IL-6 levels in patients with hypoxic gestational hypertension were significantly increased. And serum TNF-α and IL-6 levels were positively correlated with right ventricular systolic blood pressure (RVSP). Conclusion. This study revealed that the elevated levels of serum TNF-α and IL-6 are closely related to the pathophysiological process of gestational hypertension. Serum levels of TNF-α and IL-6 and ET were significantly increased, and the changes of serum TNF-α and IL-6 and ET levels had important clinical value for closely monitoring the severity of the disease and the development of the disease.

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Section: Methodsmentioning

confidence: 99%

Clinical Analysis of Echocardiography and Serum IL-6 and TNF-α Changes in Pregnant Women with Hypertension

Liu

Hou

et al. 2022

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“…For detecting HBV and HCV infections serum samples are well suited [5,175,176]. Several studies exist using either Raman spectroscopy [155,175,[177][178][179][180][181][182] or SERS [176,183] for discriminating between healthy and infected patients. From Raman spectra of serum samples also a differentiation between typhoid and dengue fever can be achieved [184].…”

Section: Study Of Host's Immune Status During Viral Infectionmentioning

confidence: 99%

“…Raman spectroscopy is another promising option for investigating the sum parameters of complex samples [1–3, 155, 166–174]. For detecting HBV and HCV infections serum samples are well suited [5, 175, 176]. Several studies exist using either Raman spectroscopy [155, 175, 177–182] or SERS [176, 183] for discriminating between healthy and infected patients.…”

Section: Virus‐host Interactionmentioning

confidence: 99%

Understanding viruses and viral infections by biophotonic methods

Ramoji

Pahlow

Pistiki

et al. 2022

Transl Biophotonics

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In the last few decades outbreaks of viral infections have often challenged the world‐wide health infrastructure and caused a significant financial burden as well as human suffering despite progress in diagnostic technologies. The recent outbreaks of the Ebola virus in the African continent, the Zika virus in the American continent, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), influenza A and lately severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral infections have repeatedly highlighted the importance of technological advancement enabling a better understanding of virions. In this review, we systematically discuss different aspects of virions and how their properties and functions can be studied using different light‐based technologies. We focus on virion classification, detection and interactions with the host's immune system. Further, the potential of advanced biophotonic methods, for example, Raman, infrared reflection, absorption and fluorescence spectroscopy, advanced microscopic techniques and biosensor‐based approaches for diagnosing viral infections, investigating therapeutics and vaccine development are described. Although significant advancements have already been made in photonic technologies, which even enable visualizing virion‐host interactions on single‐cell level, the continuous evolution of viruses demands further progress in biophotonic solutions for fast, affordable and robust health monitoring devices for screening viral infections.

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“…The following supporting information can be downloaded at: , Table S1: Findings for the JBI Critical Appraisal Tool [ 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 ].…”

mentioning

confidence: 99%

A Systematic Review of Internet of Things in Clinical Laboratories: Opportunities, Advantages, and Challenges

Munir

Akbar

Ahmed

et al. 2022

Sensors

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The Internet of Things (IoT) is the network of physical objects embedded with sensors, software, electronics, and online connectivity systems. This study explores the role of IoT in clinical laboratory processes; this systematic review was conducted adhering to the PRISMA Statement 2020 guidelines. We included IoT models and applications across preanalytical, analytical, and postanalytical laboratory processes. PubMed, Cochrane Central, CINAHL Plus, Scopus, IEEE, and A.C.M. Digital library were searched between August 2015 to August 2022; the data were tabulated. Cohen’s coefficient of agreement was calculated to quantify inter-reviewer agreements; a total of 18 studies were included with Cohen’s coefficient computed to be 0.91. The included studies were divided into three classifications based on availability, including preanalytical, analytical, and postanalytical. The majority (77.8%) of the studies were real-tested. Communication-based approaches were the most common (83.3%), followed by application-based approaches (44.4%) and sensor-based approaches (33.3%) among the included studies. Open issues and challenges across the included studies included scalability, costs and energy consumption, interoperability, privacy and security, and performance issues. In this study, we identified, classified, and evaluated IoT applicability in clinical laboratory systems. This study presents pertinent findings for IoT development across clinical laboratory systems, for which it is essential that more rigorous and efficient testing and studies be conducted in the future.

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Serum analysis method combining cellulose acetate membrane purification with surface‐enhanced Raman spectroscopy for non‐invasive HBV screening

Cited by 10 publications

References 28 publications

Clinical Analysis of Echocardiography and Serum IL-6 and TNF-α Changes in Pregnant Women with Hypertension

Clinical Analysis of Echocardiography and Serum IL-6 and TNF-α Changes in Pregnant Women with Hypertension

Understanding viruses and viral infections by biophotonic methods

A Systematic Review of Internet of Things in Clinical Laboratories: Opportunities, Advantages, and Challenges

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