Serum Blood Urea Nitrogen and Plasma Brain Natriuretic Peptide and Low Diastolic Blood Pressure Predict Cardiovascular Morbidity and Mortality Following Discharge in Acute Decompensated Heart Failure Patients

Comparison of Prognostic Value of Red Cell Distribution Width and NT-proBNP for Short-Term Clinical Outcomes in Acute Heart Failure Patients

“…29,30) The activation of neurohumoral factors of heart failure, including the sympathetic nervous system, renin-angiotensin activities, and arginine vasopressin, can elevate the level of blood urea. 31) Thus, an elevated blood urea nitrogen level could be regarded as a surrogate marker for neurohumoral activation, 32) which can explain the strong prognostic value of urea in the short-term outcome of patients of AHF.…”

Correlation of Pre- and In-Hospital Systolic Blood Pressure in Acute Heart Failure Patients and the Prognostic Implications – Report From the Tokyo Cardiac Care Unit Network Emergency Medical Service Database –

“…These factors are known to be associated with prognosis in patients with HF: prior admissions for HF; 20 anemia; 7,21,22 and BNP level. [23][24][25][26] In particular, renal impairment is a powerful prognostic factor in patients with AHF. 3 In addition, Mitsnefes et al have reported that patients with chronic renal impairment, particularly those on dialysis, have significantly low contractile reserve.…”

The prognostic combined role of B-type natriuretic peptide, blood urea nitrogen and congestion signs persistence in patients with acute heart failure

“…Although some authors examined the role of the combined BUN and BNP assay in this setting, these two biomarkers combined with clinical signs have never been evaluated before. 15 Congestion is the most important factor causing hospitalization in patients with ADHF. 16 The absence of congestion resolution is related to adverse outcome and several studies showed the central role of congestion in the pathogenesis of worsening heart failure and subsequent hospitalization.…”