Serum Carcinoembryonic Antigen as a Prognostic Factor in Resectable Gastric Cancer

Prognostic Significance of Serum and Tissue Carcinoembryonic Antigen in Patients with Gastric Adenocarcinomas

“…It has been reported that serum CEA is not associated with the location of the primary cancer (10), however, in the current study, tumors located in the lower 1/3 of the stomach had significantly higher positive rate of serum CEA than those located in the upper 1/3 or middle 1/3. The (10,17,22), and in the current study, a correlation of the expression of CEA in cancer tissues and the histological type according to the Lauren's as well as Ming's classification was not shown, nevertheless, serum CEA showed a higher positive rate in the intestinal type of the Lauren's classification than in the diffuse type, and in addition, a higher rate was detected in the expanding type of the Ming's classification. In each classification, however, mixed type had much higher CEA positive rate than other types, and this seems to cause the statistically significant difference in the serum positivity according to the Ming classification.…”

Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association

“…Ucar et al [43] reported that 9 of 11 patients (82 %) with liver metastases were positive for CA72-4. Because the positive rate for CA72-4 in patients with poorly differentiated adenocarcinoma was significantly higher than that for CEA (36 vs. 8 %), the overall positive rate for CA72-4 was higher than that for CEA [25]. In patients with Bormann type 2, 3, and 4, the positive rates for CA72-4 were higher than that for CEA.…”

Combined Detection of CEA, CA 19-9, CA 242 and CA 50 in the Diagnosis and Prognosis of Resectable Gastric Cancer

“…The preoperative serum CEA level has been reported as a useful marker in predicting gastric cancer prognosis (Gonzalez et al, 1996;Tachibana et al, 1998;Choi et al, 2006). However, Kodera et al (Kodera et al, 1996) revealed that serum CA 19-9 was better than CEA as a prognostic factor in multivariate analyses in gastric cancer patients.…”