Serum Circulating mRNA Panel for the Early Detection of Gastric Cancer: A Potential Biomarker Test
Xinyu Peng,
Xiaoyan Teng,
Qian Ma
et al.
Abstract:Circulating free messenger RNAs (cfmRNAs) in serum have emerged as potential noninvasive biomarkers for cancer diagnosis, including gastric cancer (GC). This study utilized RNA‐sequencing data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases to identify a training set of 100 differentially expressed genes (DEGs) specific to GC patients. Employing a support vector machine (SVM) classification, we narrowed down the candidate gene set to 23, which was further refined to 4 genes–DMBX… Show more
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