Serum PCT and its Relation to Body Weight Gain in Pulmonary Tuberculosis

Rohini, K.; Bhat, Surekha; Srikumar, P. S.; Kumar, Ajay

doi:10.1007/s12291-014-0432-6

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…These findings have been discussed in detail in our earlier study [9,10]. Anemia is a common hematologic complication among TB patients and is a strong risk factor for mortality [11].…”

Section: Discussionsupporting

confidence: 55%

Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients

et al. 2015

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The aim of the study was the assessment of hematological parameters in pulmonary tuberculosis patients. Forty patients diagnosed with tuberculosis were recruited from the Institute of Thoracic Medicine on the basis of history, clinical examination, chest radiography, sputum examination and related laboratory parameters and were compared with age and sex matched healthy volunteers (n = 40). Hematological parameters and CRP in tuberculosis patients were determined. The mean values for serum hemoglobin level, RBC count and platelet count in PTB was found to be less (p \ 0.001). Erythrocyte sedimentation rate (ESR), plasma C-reactive protein, WBC count in PTB subjects was increased (p \ 0.001 for ESR & CRP, p \ 0.05 for WBCs) and all were statistically significant. This study demonstrated that serum hemoglobin level, RBC count and platelet count was decreased in tuberculosis patients whereas ESR, CRP and WBC count was increased when compared with healthy controls.

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“…These findings have been discussed in detail in our earlier study [9,10]. Anemia is a common hematologic complication among TB patients and is a strong risk factor for mortality [11].…”

Section: Discussionsupporting

confidence: 55%

Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients

et al. 2015

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“…The haemogram of patients with TB varies during the treatment and type of disease. In the haemogram of patients with infiltrative tuberculosis, there was a greater severity of inflammation events, and in disseminated form -of allergic and autoimmune processes [7,8]. It exerts a dazzling variety of hematological effects involving both cell and plasma components.…”

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confidence: 99%

Specificity and sensitivity of the new test for serological evaluation of tuberculosis using MPT83-MPT63 fusion antigen

Siromolot¹,

Chudina²,

Danilova³

et al. 2018

Ukr.Biochem.J

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the aim of this work was to characterize the experimental test-system based on mPt83-mPt63 fusion antigen with reference commercial diagnostics and investigate the basic characteristics of enzyme-linked immunosorbent assay (ELISA) tests such as specificity and sensitivity. In addition, we investigated the correlation of biochemical and immunological parameters of blood samples of patients with tuberculosis, which was correctly diagnosed by those test-systems. It was shown that the developed test-system match the existing ones regarding the criteria of reliability and the basic requirements of elISA kits. recommendations for the testing of serum samples and indications for the use of the proposed serological diagnostic methods has been suggested. k e y w o r d s: diagnostic of tuberculosis, recombinant protein, elISA.

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Longitudinal body weight and sputum conversion in patients with tuberculosis, Southwest Ethiopia: a retrospective follow-up study

2018

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ObjectivesTo describe the association between change in body weight and sputum smear conversion and to identify factors linked with body weight and sputum smear conversion in Jimma University Specialized Hospital, Southwest Ethiopia.DesignA retrospective follow-up study.SettingTeaching hospital in Southwest Ethiopia.ParticipantsA total of 450 patients with tuberculosis (TB) were included in the follow-up between 2011 and 2013.Main outcome measuresThe association between body weight and sputum conversion was measured using joint modelling.ResultsThe association between change in body weight and change in sputum conversion was −0.698 (p<0.001). A strong inverse association between change in body weight and change in sputum conversion was observed. The study variables sex, age, type of TB, HIV status, dose of anti-TB drug and length of enrolment to TB treatment were significantly associated with change in body weight of patients with TB. The study variables age, type of TB, dose of anti-TB drug and length of enrolment were significantly associated with change in sputum status of patients with TB.ConclusionsAmong patients with TB who were on anti-TB treatment, increase in body weight and positive sputum status were inversely related over time. TB prevention and control strategies should give emphasis on factors such as female sex, older age, non-pulmonary positive type of TB, HIV-positive, lower dose of anti-TB drug and length of enrolment to TB treatment during monitoring of trends in body weight and sputum status.

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Serum PCT and its Relation to Body Weight Gain in Pulmonary Tuberculosis

Cited by 3 publications

References 13 publications

Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients

Assessment of Hematological Parameters in Pulmonary Tuberculosis Patients

Specificity and sensitivity of the new test for serological evaluation of tuberculosis using MPT83-MPT63 fusion antigen

Longitudinal body weight and sputum conversion in patients with tuberculosis, Southwest Ethiopia: a retrospective follow-up study

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