Serum-protein effects on the detection of the β-blocker propranolol by ion-transfer voltammetry at a micro-ITIES array

Collins, Courtney J.; Lyons, Conor; Strutwolf, Jörg; Arrigan, Damien W. M.

doi:10.1016/j.talanta.2009.10.060

Cited by 44 publications

(66 citation statements)

References 45 publications

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“…In addition to the determination of inorganic ions, ITSV was successfully applied to study lipophilic drug ions such as the β-blocker propranolol [35,36]. To the best of our knowledge, our paper is the first report about the utilization of double-polymer-modified electrodes for the quantitative detection of SSRIs.…”

Section: Introductionmentioning

confidence: 99%

Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Izadyar

Arachchige

Cornwell

et al. 2016

Sensors and Actuators B: Chemical

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Section: Introductionmentioning

confidence: 99%

Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Izadyar

Arachchige

Cornwell

et al. 2016

Sensors and Actuators B: Chemical

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“…1. The adsorption of the enzyme is mainly driven by the lipophylic interactions of the enzyme with the organic solvent [26][27][28][29][30][31][32][33][35][36][37]. It is plausible to assume that the enzyme molecules are oriented at the liquid interface, with the negatively charged surface leaning toward the aqueous phase.…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, there has been an increased attention in the study of proteins at L|L interfaces, mainly by means of the four-electrode configuration setup [26][27][28][29][30][31][32][33]. Of particular interest are electron-transfer reactions across the L|L interfaces involving redox-active enzymes.…”

Section: Introductionmentioning

confidence: 99%

Studying the ion transfer across liquid interface of thin organic-film-modified electrodes in the presence of glucose oxidase

Mirčeski

Mitrova

Ivanovski

et al. 2015

J Solid State Electrochem

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A coupled electron-ion transfer reaction at thin organic-film-modified electrodes (TFE) is studied in the presence of glucose oxidase (GOx) under voltammetric conditions. TFE consists of a graphite electrode modified with a nitrobenzene solution of decamethylferrocene (DMFC) as a redox mediator and tetrabuthylammonium perchlorate as an organic-supporting electrolyte, in contact with aqueous buffer solutions containing percholarte ions and GOx. The redox turnover of DMFC coupled with perchlorate transfer across water|nitrobenzene interface composes the coupled electronion transfer reaction. Glucose oxidase strongly adsorbs at the liquid|liquid interface affecting the coupled electron-ion transfer reaction by reducing the surface area of the liquid interface, prompting coadsorption of the transferring ion and lowering down slightly the rate of the ion transfer reaction. Although the enzyme exists as a polyvalent anion over the pH interval from 5.6 to 7, it does not participate directly in the ionic current across the liquid interface and percholrate remains the main transferring ion. Raman spectroscopic data, together with the voltammetric data collected by three-phase droplet electrodes, indicate that the adsorption of the enzyme does not depend either on the redox mediator (DMFC) or the organicsupporting electrolyte, while being driven by intrinsic interactions of the enzyme with the organic solvent. The overall electrochemical mechanism is mathematically modeled by considering linear adsorption isotherm of the transferring ion, semi-infinite mass transfer regime, and phenomenological second-order kinetic model.

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“…25) Again using DPSV, 0.05 µM propranolol could be detected even in the presence of BSA. Voltammetric sensing of protonated propranolol using arrays of nanoscale ITIES were further investigated.…”

Section: Applications Of Ities For Drug Sensingmentioning

confidence: 95%

Applications of Electrochemistry at Liquid/Liquid Interfaces for Ionizable Drug Molecule Sensing

Goh

Lee

2016

Review of Polarography

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Electrochemistry at an interface between two immiscible electrolyte solutions (ITIES) offers a great opportunity to be applied to electroanalytical, biological and energy related research fields. In particular, ion transfer processes across a polarized ITIES have been employed as powerful electrochemical ion sensing platforms. This review will highlight recent developments in addition to some challenges and future aspects on developing ion selective sensing platforms utilizing ITIES specific to ionizable pharmaceutical reagents (drugs).

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Serum-protein effects on the detection of the β-blocker propranolol by ion-transfer voltammetry at a micro-ITIES array

Cited by 44 publications

References 45 publications

Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Studying the ion transfer across liquid interface of thin organic-film-modified electrodes in the presence of glucose oxidase

Applications of Electrochemistry at Liquid/Liquid Interfaces for Ionizable Drug Molecule Sensing

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