Serum supplement in human in vitro fertilization and embryo development

Leung, Peter; Gronow, Michael; Kellow, Geoffrey N.; Lopata, Alexander; Speirs, Andrew L.; McBain, John; Plessis, Y. P.; Johnston, Ian

doi:10.1016/s0015-0282(16)47537-0

Cited by 68 publications

(14 citation statements)

References 4 publications

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“…A significantly higher pregnancy rate was seen in an in vitro fertilization program when the culture medium was supplemented with fetal cord serum than with maternal preovulatory serum [21]. In the present study, 73% of patients who achieved pregnancy had antibody attachment of > 50%, in contrast to previous findings [15] in which the pregnancy rate was greatest (67%) in couples with <50% antibody binding.…”

Section: Discussioncontrasting

confidence: 85%

Treatment of Immunological Infertility by Sperm Washing and Intrauterine Insemination

Agarwal

1992

Archives of Andrology

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The purpose of this study is to review our experience with sperm washing and intrauterine insemination as a method to reduce the presence of sperm antibodies in serum of couples with immunological infertility. Our results support the premise that sperm washing and intrauterine insemination can diminish the level of sperm-bound immunoglobulins and can improve the chance of conception in a selected group of couples with a diagnosis of immunological infertility. Patients with >50% attachment of IgG, IgA, or both antisperm antibodies in this study had a greater chance of achieving a pregnancy. The high level of antibody attachment seen in our study appears to represent true immunological infertility and therefore is more likely to respond to therapy that reduces antibody attachment and bypasses cervical mucus.

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Section: Discussioncontrasting

confidence: 85%

Treatment of Immunological Infertility by Sperm Washing and Intrauterine Insemination

Agarwal

1992

Archives of Andrology

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“…Tubal anastomosis (postinfectious) 43 Tubal anastomosis (uterotubal junction obstruction) [50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69] Tubal implantation (Reamer or cornual excision) Tubal implantation (posterior wall) Repeat tuboplasties [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] This is true if one only considers pregnancy rates when counseling patients. Invariably, numerous other factors must also be considered.…”

Section: Resultsmentioning

confidence: 99%

Reproductive Surgery vs Assisted Reproductive Technologies: Selecting the Correct Alternative

Silverberg

Hill

1991

Journal of Gynecologic Surgery

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Many innovations have been made in advanced reproductive technologies (ART) over the past several years. These procedures now yield pregnancy rates of over 20% per cycle, rates that compare favorably to many types of reproductive surgery. Therefore, ART now represents a viable alternative for many patients suffering from infertility. As these pregnancy rates continue to rise, gynecologists will have to choose between ART and reproductive surgery for a larger number of patients. This article reviews the commonly performed reproductive surgical procedures and compares expected postoperative pregnancy rates to those of ART in order to help the gynecologist make this decision.

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“…These sera were prepared following a standard serum preparation procedure, used for IVF and intrauterine insemination (IUI) [12,18,191. The sera were heat inactivated and filtered through a 0.22-pm filter prior to freezing [18,191.…”

Section: Methodsmentioning

confidence: 99%

Assessment of the Quality of Frozen Serum by Spectrophotometric Analysis and Sperm Bioassay

Hossain

Barik

Rizk

et al. 1997

Archives of Andrology

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Serum supplement in human in vitro fertilization and embryo development

Cited by 68 publications

References 4 publications

Treatment of Immunological Infertility by Sperm Washing and Intrauterine Insemination

Treatment of Immunological Infertility by Sperm Washing and Intrauterine Insemination

Reproductive Surgery vs Assisted Reproductive Technologies: Selecting the Correct Alternative

Assessment of the Quality of Frozen Serum by Spectrophotometric Analysis and Sperm Bioassay

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