Serum Uric Acid Its Correlation With Outcomes of Myocardial Infarction

Abstract

BACKGROUND The role of serum uric acid in cardiovascular and renal diseases has been intensively investigated. High serum uric acid has been indicated as a risk factor for CAD and as an independent prognostic factor of poorer outcomes in patients with verified CAD. MATERIALS AND METHODS Study was done in one hundred patients with myocardial infarction admitted at Government Rajaji Hospital, Madurai. Detailed history and clinical examination done. Uric acid was estimated. The relationship of uric acid with severity of myocardial infarction, treatment response, ejection fraction, arrhythmia and hypotension were studied. RESULTS A total of 100 patients was recruited to the study. The mean age and mean uric acid level of the study sample was 56 years and 5.9 mg/dL, respectively. There were 65 (65%) males and 35 (35%) females. Males had higher uric acid level than females (p<0.05). Those who had SUA >7 mg/dL (n=17) had low ejection fraction, which was statistically significant p value, 0.03. Among the 15 patients belonging to KILLIP IV, 12 had SUA values more than 7 mg/dL (p<0.05). CONCLUSION Measuring serum uric acid level at admission for acute myocardial infarction patients we can stratify them and can treat effectively.