2023
DOI: 10.21203/rs.3.rs-2520298/v1
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Sesame oil affect learning and memory impairment, anxiety and biomarkers of oxidative stress in rats with a long-term high-fat diet consumption

Abstract: Nowadays, high-fat foods are eaten in most societies, which causes memory impairment and anxiety through the oxidative stress pathway. Sesame oil (SO) has potential antioxidant properties. The hypothesis of this study was that sesame oil affect memory impairment and anxiety caused by a high-fat diet (HFD) in male rats. Eighty male Wistar rats were divided into eight groups (n = 10): control (standard diet; SD), the HFD, SD + SO (0.5, 1, or 2 ml/kg; once/day, gavage), and HFD + SO (0.5, 1, or 2 ml/kg; once/day,… Show more

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