Sesquiterpenoids from the barks and roots of <i>Michelia alba</i> collected in Xuan Mai town, Hanoi City, Viet Nam

Nine compounds including ursolic acid (1), esculentic acid (2), 2‐O‐trans‐p‐coumaroyl alphitolic acid (3), a mixture of (6S,7Z,9S)‐6,9‐dihydroxy‐7‐megastigmen‐3‐one (4) and (‐)‐boscialin (5), astragalin (6), tiliroside (7), 2‐phyten‐1‐ol (8), 4‐[3’‐(hydroxymethyl)oxiran‐2’‐yl]‐2,6‐dimethoxyphenol (9) were isolated from the twigs and leaves of Elaeagnus latifolia L. The elucidation of the above compounds was supported by means of modern spectroscopic methods (MS, NMR) and comparison with the reported data. It is the first time compounds 1‐9 have been isolated from Elaeagnus latifolia. For the first time, compound 4 was isolated from plant.

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The first phytochemical study of Elaeagnus latifolia in Vietnsam

Thảo

Luu

Linh

et al. 2021

Vietnam Journal of Chemistry

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Phytochemistry and anti‐inflammatory activity of iridoids from Dolichandrone spathacea collected in the mangrove forest of Phu Loc district, Thua Thien Hue province, Vietnam

Thao,

Chi,

Luu

et al. 2021

Vietnam Journal of Chemistry

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From the leaves and barks of Dolichandrone spathacea collected in the mangrove forest of Hue province, three iridoids {6‐O‐[(E)‐4‐methoxy cinnamoyl]catalpol (1), 6‐O‐[(E)‐3,4‐dimethoxy cinnamoyl]catalpol (2), nemoroside (3)} and three ursane‐type triterpenoids [ursolic acid (4), pomolic acid (5), uncaric acid (6)] were isolated and structurally elucidated. Besides, succrose octaacetate (7), daucosterol tetraacetate (8) and 1‐hentriacontanol (9) were identified from the fruits of this mangrove species. It is the first time compounds 6, 7, 9 were isolated from Dolichandrone spathacea. The main constituents of this plant, iridoids 1 and 2, were tested for the inhibition of IL‐6, TNF‐α factors and NO production. The anti‐inflammatory activity as well as the phytochemistry of the fruits of this species are reported for the first time.

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Theoretical Evaluation of Michelia Species’ Bioactive Compounds and Theraupetic Potential: A Literature Review

Oktaviana,

Isnaini,

Harnelly

et al. 2023

Grimsa J. Sci. Eng. Technol.

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Michelia alba is a multifunctional plant found in Indonesia and is also called magnolia. Michelia alba is a tree known for its essential oil, which has long been used as a fragrance ingredient in perfumes and cosmetics. The potential of M. alba is immense for use in the prevention and treatment of disease as well as the management of human health and wellness. To date, there have been few publications regarding the biological activities of M. alba, focusing on tyrosinase inhibitory, antibacterial, antidiabetic, anti-inflammatory and antioxidant activities. However, M. alba may have additional undiscovered biological activities associated with its bioactive compounds. The purpose of this literature review research is to find out the bioactive compounds and therapeutic potential of the M. alba plant through literature searches that can be a reference for further research. The literature review method is carried out by searching and collecting data from literature sources obtained from several national and international journals that review bioactive compounds and the therapeutic potential of M. alba plants. Based on the literature review, it was found that M. alba has bioactive compounds namely linalool (72.8 flower oil and 80.1% leaf oil), α-terpineol (6.04% flower oil), phenylethyl alcohol (2.58% flower oil), β-pinene (2.39% flower oil) and geraniol (1, 23%) which have therapeutic activities such as mental health disorders, anticancer, anti-inflammatory, antihypertensive, antidiabetic, antihyperlipidemia, antimaagic, antidiarrheal, anti-asthma, and antihyperpigmentation. In traditional medicine it is used to treat fever, syphilis, gonorrhea and malaria, bronchitis, prostatitis, cancer, headache, sinusitis, cough, inflammation of the respiratory tract, chest fullness, flatulence, nausea, body and underarm odor, and vaginal discharge.

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Sesquiterpenoids from the barks and roots of Michelia alba collected in Xuan Mai town, Hanoi City, Viet Nam

Cited by 3 publications

References 12 publications

The first phytochemical study of Elaeagnus latifolia in Vietnsam

The first phytochemical study of Elaeagnus latifolia in Vietnsam

Phytochemistry and anti‐inflammatory activity of iridoids from Dolichandrone spathacea collected in the mangrove forest of Phu Loc district, Thua Thien Hue province, Vietnam

Theoretical Evaluation of Michelia Species’ Bioactive Compounds and Theraupetic Potential: A Literature Review

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