Severe acquired subglottic stenosis in children: analysis of clinical features and surgical outcomes based on the range of stenosis

Morita, Keiichi; Yokoi, Akiko; Bitoh, Yuko; Fukuzawa, Hiroaki; Okata, Yuichi; Iwade, Tamaki; Endo, Kazuhira; Takemoto, Junkichi; Tamaki, Akihiko; Murakami, Kosaku

doi:10.1007/s00383-015-3773-1

Cited by 9 publications

(7 citation statements)

References 11 publications

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“…3 Similarly, no significant difference was reported in regard to gender by Morita et al in 33 pediatric patients (16 male/17 female). 9 In our study, gender had no effect on the development of SGS, in accordance with literature. Many studies on post-intubation SGS have been conducted primarily on premature babies because of their long intubation periods 5,10 ; however, the state of maturity had no effect on the development of SGS as shown in our patients.…”

Section: Discussionsupporting

confidence: 92%

“…3 Similarly, the study by Morita et al, conducted on 33 pediatric patients, reported that 29 patients had grade 3 SGS. 9 In our study, 50% of our patients showed grade 3 stenosis, which is similar to the literature.…”

Section: Discussionsupporting

confidence: 91%

“…The study of Rodriguez et al on 71 pediatric patients who developed post‐intubation SGS reported no difference among patients in terms of gender (40 male / 31 female) . Similarly, no significant difference was reported in regard to gender by Morita et al in 33 pediatric patients (16 male/17 female) . In our study, gender had no effect on the development of SGS, in accordance with literature.…”

Section: Discussionsupporting

confidence: 91%

“…Reviewing the literature, there are some studies that address follow‐up and surgical techniques in patients who have developed post‐intubation SGS. However, there are only a limited number of studies that have investigated the risk factors contributing to the development of SGS in intubated patients …”

mentioning

confidence: 99%

“…However, there are only a limited number of studies that have investigated the risk factors contributing to the development of SGS in intubated patients. [6][7][8][9] The aim of this study was to evaluate patients who were diagnosed with post-intubation SGS and to identify the risk factors contributing to the development of stenosis.…”

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confidence: 99%

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Post‐intubation subglottic stenosis in children: Analysis of clinical features and risk factors

Çakır

Atabek

Çalım

et al. 2020

Pediatrics International

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Background Subglottic stenosis (SGS) is a complication that develops after intubation and is characterized by respiratory distress. The aim was to evaluate patients with post‐intubation SGS and to discover the factors contributing to its development. Methods A total of 112 patients who had a history of intubation were included. The case group consisted of 50 patients with post‐extubation persistent respiratory symptoms for which flexible bronchoscopy (FOB) was conducted and showed SGS. The control group consisted of 62 patient with no post‐extubation persistent respiratory symptoms, for whom FOB was not done (n = 54), and who had post‐extubation persistent respiratory symptoms and underwent FOB, which did not show subglottic stenosis (n = 8). Results No significant differences were detected related to age, gender, and gestational age. The median number of recurrent intubations was 2.5 and 3 in the case group and in control group, respectively (P = 0.14). The median duration of intubation was 20.5 days in the case group, and 6 days in the control group (P < 0.001). The Myer–Cotton classification indicated a degree of obstruction of grade 1 (mild) in 30% (n = 15), grade 2 in 16% (n = 8), grade 3 in 48% (n = 24), and grade 4 in 6% (n = 3) of the case group. Conclusion The duration of intubation was found to be a significant risk factor for SGS development. Age at intubation, gender, gestational age, indication of intubation, and the number of recurrent intubations were found to have no significant association. Patients with post‐extubation persistent respiratory problems, especially those with prolonged intubations, should be evaluated for SGS.

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