Severe hypomagnesaemia as new potential stroke mimic: a case report

Hypomagnesaemia Induced Reversible Cerebellar Syndrome

“…6 The features of this include symptom onset where magnesium is <0.2mmol/L, corresponding hypocalcaemia, plus symptoms of bilateral nystagmus, gait ataxia and dysarthria described in this case. 6,[9][10] Other features not present here include seizures, cognitive impairment and oedema affecting both cerebellar hemispheres revealed by MR imaging. 6,9 Rapid correction of magnesium typically leads to an improvement in cerebellar symptoms.…”

“…6,[9][10] Other features not present here include seizures, cognitive impairment and oedema affecting both cerebellar hemispheres revealed by MR imaging. 6,9 Rapid correction of magnesium typically leads to an improvement in cerebellar symptoms. 6 Previous literature reviews have found that diagnosis of hypomagnesaemia induced cerebellar disease has been delayed.…”

“…[6][7] Magnesium deficiency may cause cardiac dysrhythmias, 1 in addition to a variety of neurological signs such as muscle weakness, 8 muscle cramps, spasm, tremor, seizures and athetosis. 1,6,[9][10] Low magnesium may also produce secondary pathologies relating to other electrolyte imbalances due to its role in enzyme ligand formation in cation transport across the cellular membrane. 1 Hypokalemia and intracellular accumulation of sodium and calcium may result as these ions decrease down their concentration gradients when active transport systems such as Na-K-ATPase are impaired.…”