Sexually transmitted infections: progress and challenges since the 1994 International Conference on Population and Development (ICPD)

Ortaylı, Nuriye; Ringheim, Karin; Collins, Lynn H.; Sladden, Tim

doi:10.1016/j.contraception.2014.06.024

Cited by 25 publications

(23 citation statements)

References 38 publications

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“…Según datos registrados en el 2008, eran tres los continentes que presentaban la mayor incidencia de sífilis, en donde América ocupaba el tercer lugar registrando 2,8 millones de casos (1).…”

Section: Introductionunclassified

Infecciones de transmisión sexual en mujeres de edad fértil usuarias del Hospital Regional de Villa Hayes, Paraguay

Gómez

Valenzuela

Orihuela³

et al. 2015

Mem. Inst. Investig. Cienc. Salud

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Las Infecciones de Transmisión Sexual (ITS) se encuentran entre las cinco razones de consulta más frecuente en adultos. En Paraguay existe un conocimiento limitado sobre frecuencia de ITS especialmente en mujeres no gestantes en edad fértil. Por ello, este estudio piloto descriptivo de corte transverso analizó la frecuencia de sífilis, de infección por el Virus de la Inmunodeficiencia Humana (VIH) de factores de riesgo asociados en 100 mujeres en edad fértil (18-48 años) no gestantes que acudieron al Hospital Regional de Villa Hayes. La detección de sífilis se realizó mediante el método inmunocromatográfico y la confirmación por la Prueba de Absorción de Anticuerpos Treponémicos Fluorescentes. La infección por VIH fue detectada mediante el método inmunocromatográfi-co y el Ensayo por Inmunoabsorción Ligado a Enzimas. Se consideró un conocimiento aceptable sobre prevención y transmisión de estas ITS si el 60% de las preguntas se contestaban correctamente. Se observó una alta frecuencia de sífilis, de 13% (IC 95% 7,1 -21,2%) y una asociación entre el bajo nivel educativo y la presencia de sífilis (p=0,002). No se encontró ningún resultado positivo para VIH. El 11% de las mujeres presentó un nivel inaceptable de conocimiento, sin embargo se evidenció una alta frecuencia de mujeres (58%) que no utilizaba preservativo, lo cual indica falta de buenas prácticas. Es preciso fortalecer las medidas de control y manejo de ITS ya existentes en esta región especialmente en las mujeres no gestantes en edad fértil.Palabras clave: Sífilis, VIH, factores de riesgo, conocimiento, mujeres en edad fértil. Infecciones de transmisión sexual en mujeres de edad fértil usuarias

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Section: Introductionunclassified

Infecciones de transmisión sexual en mujeres de edad fértil usuarias del Hospital Regional de Villa Hayes, Paraguay

Gómez

Valenzuela

Orihuela³

et al. 2015

Mem. Inst. Investig. Cienc. Salud

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“…Sexually Transmitted Infections (STIs) cause considerable mortality and morbidity in both adults and new-borns and expedite the transmission of Human Immunodeficiency Virus (HIV) infection [1]. They are spread principally by sexual contact, including vaginal, anal and oral sex.…”

Section: Introductionmentioning

confidence: 99%

“…The estimated annual incidence of non-HIV STIs has increased by nearly 50% during the period 1995-2008. The growth in STIs has been aggravated by lack of accurate, inexpensive diagnostic tests and absence of surveillance and reporting systems in the majority of countries among other factors [1]. The largest proportion of STIs occur in developing nations, led by South and Southeast Asia, followed by sub-Saharan Africa, Latin America, and the Caribbean [4].…”

Section: Introductionmentioning

confidence: 99%

“…They are spread principally by sexual contact, including vaginal, anal and oral sex. STIs can also be spread through non-sexual means such as via blood or blood products and from mother to child during pregnancy and child birth [1]. Marginalized populations with highest rates for STIs like sex workers, drug users, men who have sex with men and adolescents have limited access to adequate health care services [2].…”

Section: Introductionmentioning

confidence: 99%

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Sexually Transmitted Illnesses in Masvingo Province, 2012-2015: A Secondary Data Analysis

Hwami¹,

Juru²,

Shamu³

et al. 2017

OJEpi

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“…Bacteria were very small and harmful organism, some bacteria could cause various types of infectious diseases such as typhoid [1], common cold [2], influenza [3], pneumonia [4], malaria [5], amebiasis [6], syphilis and AIDS [7]. Bacteria may be innate resistant or acquire resistance to one or few classes of antimicrobial agents.…”

Section: Introductionmentioning

confidence: 99%

In Vitro and in Silico Antibacterial Activity of 1.5-BIS (3’-Ethoxy-4’-Hydroxyphenyl)-1-4-Pentadiene-3-One

Purwanggana

Mumpuni

Mulatsari

2018

Int J Pharm Pharm Sci

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Objective: The main objective of this research were screened in vitro and in silico of 1,5-bis (3'-ethoxy-4'-hydroxyphenyl)-1,4-pentadiene-3-one as potential antibacterial agents. Methods:The in vitro antibacterial study was carried against Staphylococcus aureus, Staphylococcus epidermidis (gram positive) and Escherichia coli, Salmonella thypi (gram negative) using broth dilution method to determine Minimum Inhibitory Concentration (MIC), disc diffusion method to determine the diameter of inhibition zone. In silico antibacterial study was carried using computational software Protein-Ligand ANT System (PLANTS), computational docking was carried using receptor with Protein Data Bank (PDB) file 3MZD. The structures were optimized prior docking using YASARA, and MarvinSketch. The results of antibacterial testing were compared to two positive control drugs i. e amoxicillin and cefadroxil. Results:In vitro evaluation showed that 1,5-bis (3'-ethoxy-4'-hydroxyphenyl)-1,4-pentadiene-3-one has a better antibacterial activity than amoxicillin and cefadroxil with a Minimum Inhibitory Concentration (MIC) of 0.15 ppm and diameter of inhibition zone of 11.27±0.31, 11.35±0.39, 11.25±0.33, and 11.05±0.45 mm in Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Salmonella thypi, respectively. These results in line with in silico evaluation that showed 1,5-bis (3'-ethoxy-4'-hydroxyphenyl)-1,4-pentadiene-3-one has more negative docking score than amoxicillin, cefadroxil, and cloxacillin acyl as a native ligand on the 3MZD receptor. Conclusion:This results obtained in this research work were 1,5-bis (3'-ethoxy-4'-hydroxyphenyl)-1,4-pentadiene-3-one compound potential as an antibacterial agent.

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Sexually transmitted infections: progress and challenges since the 1994 International Conference on Population and Development (ICPD)

Cited by 25 publications

References 38 publications

Infecciones de transmisión sexual en mujeres de edad fértil usuarias del Hospital Regional de Villa Hayes, Paraguay

Infecciones de transmisión sexual en mujeres de edad fértil usuarias del Hospital Regional de Villa Hayes, Paraguay

Sexually Transmitted Illnesses in Masvingo Province, 2012-2015: A Secondary Data Analysis

In Vitro and in Silico Antibacterial Activity of 1.5-BIS (3’-Ethoxy-4’-Hydroxyphenyl)-1-4-Pentadiene-3-One

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