Shear-induced diffusion in a red blood cell suspension

Srivastav, Aparna; Grandchamp, Xavier; Coupier, Gwennou; Podgorski, Thomas

doi:10.1080/10255842.2012.713650

Cited by 2 publications

(1 citation statement)

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“…Such an effect contributes to the pronounced phenomenon of margination in blood microvasculature where red blood cells (RBCs) migrate toward the vascular center leaving the cell-free layer near the vascular wall 226 . Similarly, SID also leads to resuspension of particles in crossflow filtration systems 224,227 and defocusing of cells in some microfluidic flow systems 228,229 …”

Section: Sorting By Shear Induced Diffusionmentioning

confidence: 99%

Label-free microfluidic sorting of microparticles

et al. 2019

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Massive growth of the microfluidics field has triggered numerous advances in focusing, separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems capable of performing these functions are rapidly finding applications in industrial, environmental, and biomedical fields. Passive and label-free methods are one of the major categories of such systems that have received enormous attention owing to device operational simplicity and low costs. With new platforms continuously being proposed, our aim here is to provide an updated overview of the state of the art for passive label-free microparticle separation, with emphasis on performance and operational conditions. In addition to the now common separation approaches using Newtonian flows, such as deterministic lateral displacement, pinched flow fractionation, cross-flow filtration, hydrodynamic filtration, and inertial microfluidics, we also discuss separation approaches using non-Newtonian, viscoelastic flow. We then highlight the newly emerging approach based on shear-induced diffusion, which enables direct processing of complex samples such as untreated whole blood. Finally, we hope that an improved understanding of label-free passive sorting approaches can lead to sophisticated and useful platforms toward automation in industrial, environmental, and biomedical fields.

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Section: Sorting By Shear Induced Diffusionmentioning

confidence: 99%