Shewanella algae Infections in United States Naval Special Warfare Trainees

Bauer, Matthew; Stone-Garza, Kristi; Croom, Daniel; Andreoli, Cheryl; Woodson, Peter; Graf, Paul C. F.; Maves, Ryan C

doi:10.1093/ofid/ofz442

Cited by 12 publications

(7 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent advances in the taxonomy and phylogenetic relatedness of Shewanella spp. supported the concept that most human infections were caused by S. algae [5,8].…”

Section: Introductionmentioning

confidence: 61%

Genomic analysis reveals high intra-species diversity of Shewanella algae

Huang

et al. 2022

Microbial Genomics

View full text Add to dashboard Cite

Shewanella algae is widely distributed in marine and freshwater habitats, and has been proved to be an emerging marine zoonotic and human pathogen. However, the genomic characteristics and pathogenicity of Shewanella algae are unclear. Here, the whole-genome features of 55 S . algae strains isolated from different sources were described. Pan-genome analysis yielded 2863 (19.4 %) genes shared among all strains. Functional annotation of the core genome showed that the main functions are focused on basic lifestyle such as metabolism and energy production. Meanwhile, the phylogenetic tree of the single nucleotide polymorphisms (SNPs) of core genome divided the 55 strains into three clades, with the majority of strains from China falling into the first two clades. As for the accessory genome, 167 genomic islands (GIs) and 65 phage-related elements were detected. The CRISPR-Cas system with a high degree of confidence was predicted in 23 strains. The GIs carried a suite of virulence genes and mobile genetic elements, while prophages contained several transposases and integrases. Horizontal genes transfer based on homology analysis indicated that these GIs and prophages were parts of major drivers for the evolution and the environmental adaptation of S. algae . In addition, a rich putative virulence-associated gene pool was found. Eight classes of antibiotic-associated resistance genes were detected, and the carriage rate of β-lactam resistance genes was 100 %. In conclusion, S. algae exhibits a high intra-species diversity in the aspects of population structure, virulence-associated genes and potential drug resistance, which is helpful for its evolution in pathogenesis and environmental adaptability.

show abstract

“…Recent advances in the taxonomy and phylogenetic relatedness of Shewanella spp. supported the concept that most human infections were caused by S. algae [5,8].…”

Section: Introductionmentioning

confidence: 61%

Genomic analysis reveals high intra-species diversity of Shewanella algae

Huang

et al. 2022

Microbial Genomics

View full text Add to dashboard Cite

show abstract

“…However, prior reports of monomicrobial infection with S. algae have suggested the organism as causal in many cases, confirming its ability to cause disease [28][29][30]. Although infection in healthy hosts is uncommon, rare cases have been reported in individuals with no underlying diseases due to massive exposure to marine environment and seafood consumption [31][32][33]. The increased in S. algae virulence was attributed to its hemolytic activity, enzymatic activity, and biofilm formation [18,34,35].…”

Section: Introductionmentioning

confidence: 95%

Characterization of putative pathogenic Shewanella algae isolated from ballast water

et al. 2021

View full text Add to dashboard Cite

Background and Aim: Shewanella algae is ubiquitous in marine-associated environments and has been increasingly recognized as a significant human pathogen that can cause serious infections mainly associated with exposure to seawater and ingestion of raw seafood. This study aimed to isolate and characterize S. algae from ballast water of ships berthed at Port Klang, Malaysia. Materials and Methods: Ballast water was sampled from nine ships docked at Port Klang, Malaysia. The isolates were identified and characterized based on biochemical and enzymatic properties, 16S rRNA and gyrB sequencing, biofilm formation capability, and antibiotic susceptibility. Results: A total of four S. algae isolates were isolated from four ballast water samples tentatively name Sa-BW1, Sa-BW2, Sa-BW7, and Sa-BW8. All isolates showed positive reaction for cytochrome oxidase, catalase, high tolerance to NaCl (6% and 8%), ability to grow at 42°C, and on Salmonella-Shigella agar. The strains also exhibited β-hemolytic activity on sheep blood and human blood agar, positive reaction for lipase, protease, DNase and gelatinase, strong biofilm adherence capabilities and multiple antibiotic resistances against ampicillin, carbenicillin, cephalothin, colistin, novobiocin, oxacillin, penicillin, rifampicin, and tobramycin which suggested their potential pathogenicity. Conclusion: This study demonstrated the occurrence of putative pathogen S. algae in ballast water of ships docked at Malaysian port.

show abstract

“…23 Other studies have also reported variable resistance to ampicillin and cephalosporins in this species. 31 The antibiotic sensitivity report for our patient indicated that the strain of S. algae isolated from patient was susceptible to all β-lactam antibiotics.…”

Section: Discussionmentioning

confidence: 70%

Rare Cause of Soft Tissue Infection: Shewanella algae

Yılık,

Akgül,

Gençeli

et al. 2024

J Pediatr Infect Dis

View full text Add to dashboard Cite

Shewanella algae is a common microorganism in nature, but a rare pathogen in humans. It is a causative agent of skin and soft tissue infections, especially in patients with skin ulcers or trauma. S. algae can enter the body through the eyes, ears, gastrointestinal tract, or respiratory tract. Immunocompromised individuals are at increased risk of developing bacteremia and sepsis from the infection. This report presents a case of posttraumatic soft tissue infection caused by S. algae in an 18-year-old male after swimming in the sea. The bacteria were cultured from the wound site.

show abstract

Shewanella algae Infections in United States Naval Special Warfare Trainees

Cited by 12 publications

References 9 publications

Genomic analysis reveals high intra-species diversity of Shewanella algae

Genomic analysis reveals high intra-species diversity of Shewanella algae

Characterization of putative pathogenic Shewanella algae isolated from ballast water

Rare Cause of Soft Tissue Infection: Shewanella algae

Contact Info

Product

Resources

About