Short Bowel Syndrome

Wilmore, Douglas W.; Robinson, Malcolm K.

doi:10.1007/s002680010266

Cited by 65 publications

(38 citation statements)

References 21 publications

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“…Despite several treatment options, such as long-term parenteral nutrition, intestinal rehabilitation, various intestinal lengthening procedures, and, more recently, small bowel transplantation, the outcomes with current therapies are still not optimal for patients with SBS [1][2][3][4]. Preserving the distal ileum with the ileocecal junction in patients undergoing massive small bowel resection is associated with better surgical outcomes; however, the adaptive mechanisms occurring in the distal ileum for improving nutrient absorption, and especially for proteins as peptides, has not been characterized.…”

Section: Discussionmentioning

confidence: 99%

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Peptide absorption after massive proximal small bowel resection: Mechanisms of ileal adaptation

Qandeel

Hernandez

Alonso

et al. 2009

Journal of the American College of Surgeons

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Section: Discussionmentioning

confidence: 99%

“…Extensive operative resection of the small intestine can be imperative in the management of several pathologic conditions but may result in the devastating malabsorptive state of "short bowel syndrome (SBS)" [1][2]. A similar state can follow traumatic loss of intestinal surface area, also leading to SBS.…”

Section: Introductionmentioning

confidence: 99%

Peptide absorption after massive proximal small bowel resection: Mechanisms of ileal adaptation

Qandeel

Hernandez

Alonso

et al. 2009

Journal of the American College of Surgeons

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“…Wilmore i wsp. [40] oraz Byrne i wsp. [41] zaobserwowali, że glutamina podawana dojelitowo (dawki odpowiednio 30 g/dobę i 0,6 g/kg/dobę wraz z podawanym podskórnie hormonem wzrostu w ilości 0,03-0,14 mg/kg/dobę) w stosunku do żywienia dojelitowego bez glutaminy poprawia wchłanianie składników odżywczych (o 39%) i powoduje zmniejszenie ilości wydalanego stolca (o 33%).…”

Section: Zespół Krótkiego Jelitaunclassified

Nutritional support with glutamine according to recommendations of the European Society for Clinical Nutrition and Metabolism (ESPEN)

Kędziora¹,

Słotwiński²,

Dąbrowska³

2010

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StreszczenieW stanach stresu metabolicznego (np. urazy, zapalenia, oparzenia, choroby nowotworowe, kacheksja) glutamina wykorzystywana jest jako źródło energii w większych ilościach niż w stanie fizjologicznym i staje się związkiem warunkowo niezbędnym. Dlatego też w takich sytuacjach zalecana jest jej suplementacja. Europejskie Towarzystwo Żywienia Klinicznego i Metabolizmu (ESPEN) od 2005 r. przedstawia zalecenia żywieniowe dotyczące pozajelitowego lub dojelitowego stosowania glutaminy w poszczególnych jednostkach chorobowych i konkretnych sytuacjach klinicznych. Niniejsza praca ma na celu zebranie i uporządkowanie aktualnych zaleceń ESPEN dotyczących suplementacji tego aminokwasu zarówno w żywieniu enteralnym, jak i parenteralnym. AbstractIn conditions of metabolic stress (trauma, burns, cancer, cachexia) glutamine as a source of energy is used more than in the physiological state and becomes a conditionally essential amino acid. Because of this, glutamine should be supplemented in these conditions. The European Society for Clinical Nutrition and Metabolism (ESPEN) since 2005 has presented recommendations of glutamine's use in different diseases and clinical states. This article presents current recommendations of glutamine supplementation in both enteral and parenteral nutrition.

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“…Após ressecção maciça do intestino delgado o tratamento precoce é direcionado para o controle da diarréia, reposição de líquidos e instituição de nutrição parenteral total (NPT). Outras medidas importantes incluem a redução da secreção gástrica com antagonistas do receptor H2 ou bloqueadores da bomba de prótons, suplementação de potássio, cálcio, zinco e particularmente magnésio de acordo com a monitoração dos níveis séricos 1,9,21,22,23,33,34 . O análogo da somatostatina de ação longa, octreotídeo, parece reduzir a quantidade de diarréia durante a fase inicial da SIC.…”

Section: Introductionunclassified

Síndrome do intestino curto: uma nova alternativa de tratamento cirúrgico

Franzon¹,

Suzuki²,

Sato³

et al. 2010

ABCD, arq. bras. cir. dig.

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DESCRITORES -Síndrome do intestino curto. Nutrição parenteral total. Cirurgia.RESUMO -Introdução -A síndrome do intestino curto resulta de comprimento total de intestino delgado inadequado para manter a nutrição, e assim, os pacientes tornam-se cronicamente dependentes de nutrição parenteral total. Numerosas estratégias cirúrgicas foram estudadas para restabelecer a função intestinal normal. Objetivo -Propor a utilização da inversão de segmento de alça associada à STEP -Serial Transverse Enteroplasty -para aumentar a área absortiva intestinal em pacientes com síndrome do intestino curto. Método -Os autores descrevem uma nova alternativa para o tratamento cirúrgico da síndrome do intestino curto, demonstrando sua facilidade e eficiência para o objetivo proposto. Resultados -As duas técnicas associadas permitiram alongar a alça intestinal em 2,6 vezes do comprimento original, com posterior ganho de peso, redução do número de evacuações para uma exoneração ao dia e melhora da qualidade de vida social e psicológica. Conclusão -Essa técnica de inversão de segmento de alça intestinal e posterior STEP surge como tratamento eficiente e definitivo à síndrome do intestino curto de forma promissora e segura permitindo retorno à alimentação por via oral com satisfatória absorção de nutrientes e ganho de peso, retorno da motilidade efetiva intestinal, associada à baixa morbidade e melhoria da qualidade de vida social e psicológica. Apesar de requerer várias cargas de grampeadores lineares apresenta baixa morbidade e passa a tornar-se um potencial substituto para o transplante intestinal.ABSTRACT -Background -The short bowel syndrome results of inadequate total length of small intestine that is not enough to nutrition, and so, the patients become dependents of total parenteral nutrition. Numerous surgical strategies had been studied to reestablish the normal intestinal function. ObjectiveConsider the inversion segment of small intestine associated with STEP -Serial Transverse Enteroplasty -to increase the intestinal absorptive area in patients with short bowel syndrome. Method -The authors describe a new alternative for surgical treatment of short bowel syndrome, demonstrating it's easiness and efficiency for the considered objective. Results -The two techniques associated, had allowed lengthening the small intestine in 2,6 times the original length, with posterior profit of weight, reduction the number of evacuations. ConclusionThis technique of inversion segment of small intestine and posterior STEP is efficient, appears as definitive and promising technique of treatment to short bowel syndrome allowing return to oral feeding, with satisfactory absorption of nutrients, return to normal intestinal movement, associated to low morbidity and improvement the quality of social and psychological life. It presents low morbidity and is a potential substitute to intestinal transplant. INTRODUÇÃOA síndrome do intestino curto (SIC) resulta de um comprimento total de intestino delgado que é inadequado para manter a nutrição via oral sat...

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Short Bowel Syndrome

Cited by 65 publications

References 21 publications

Peptide absorption after massive proximal small bowel resection: Mechanisms of ileal adaptation

Peptide absorption after massive proximal small bowel resection: Mechanisms of ileal adaptation

Nutritional support with glutamine according to recommendations of the European Society for Clinical Nutrition and Metabolism (ESPEN)

Síndrome do intestino curto: uma nova alternativa de tratamento cirúrgico

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