Short-duration multiple-session subthreshold micropulse yellow laser (577 nm) for chronic central serous chorioretinopathy: results at 3 years

Kim, Yang Jae; Kim, Si Yeol; Ha, Seunggyun; Moon, Daruchi; Seong, San; Kwon, Oh Woong; Park, Han Sang

doi:10.1038/s41433-018-0309-7

Cited by 18 publications

(12 citation statements)

References 29 publications

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“…We followed a similar SMPL protocol as that described in previous reports. 8,9 We increased the duty cycle and duration after the first session of SMPL on the aneurysmal lesion more repeatedly to expect closure of aneurysm. After treatment, the involution of aneurysm was achieved; however, it was not clear whether it means preclinical nonexudative stage PVAC stage or complete resolution.…”

Section: Discussionmentioning

confidence: 99%

Multiple-Session Subthreshold Micropulse Laser Therapy for Exudative Perifoveal Vascular Anomalous Complex: A Case Report

Kang

Park

2021

RETINAL Cases &Amp; Brief Reports

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Section: Discussionmentioning

confidence: 99%

Multiple-Session Subthreshold Micropulse Laser Therapy for Exudative Perifoveal Vascular Anomalous Complex: A Case Report

Kang

Park

2021

RETINAL Cases &Amp; Brief Reports

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“…e photocoagulation energy for each patient was titrated at the nasal upper quadrant of the retina in the monospot micropulse model. e power titration would be gradually increased until a visible burn was seen, and then, the power was reduced by 50% for individual treatment (Figure 1, 1(a)-1(f) [9][10][11][12]. For the half-dose PDT group, patients received an intravenous infusion of 3 mg/m 2 verteporfin (Visudyne, Novartis, Basel, Switzerland) delivered over a period of 10 minutes and the treatment was ICGA-guided and performed 15 min after the start of the infusion.…”

Section: Methodsmentioning

confidence: 99%

Subthreshold Micropulse Treatment Laser versus Half-Dose Photo Dynamic Therapy for the Chronic Central Serous Chorioretinopathy with Parafoveal or Subfoveal Leakage STML versus PDT for Treatment of Chronic CSC

Chen

Zhao

Yin

et al. 2022

Journal of Ophthalmology

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Purpose. The study aimed to compare the efficacy and safety outcomes of a subthreshold micropulse treatment laser (SMTL) versus half-dose photodynamic therapy (PDT) for treatment of chronic central serous chorioretinopathy (cCSC) with parafoveal or subfoveal leakage to persistent subretinal fluid. Methods. One hundred and forty-eight patients (148 eyes) with persistent cCSC were enrolled in this retrospective study and treated with SMTL or half-dose PDT. All patients were diagnosed according to clinical characteristics and findings on multimodal imaging. The medical records including patients with a minimum follow-up period of 3 months were reviewed. The patients were divided into two groups according to the application of the SMTL or PDT. The group of the SMTL or PDT was also divided into two subgroups according to parafoveal or subfoveal leakage. The primary outcomes included best-corrected visual acuity (BCVA) and central retinal thickness (CRT) before and 1, 2, and 3 months after treatment. The repeat treatment and resolution of subretinal fluid were also collected. Results. Seventy-nine patients (79 eyes) treated with half-dose PDT and 69 Patients (69 eyes) treated with the STML were included. The mean age was 44.20 ± 7.42 years and 80% were male. No significant difference in age, gender, baseline logMAR BCVA or CRT between the half-dose PDT group and the SMTL group ( P = 0.201 ; 0.051) can be defined. The BCVA of the SMTL group improved at 1, 2, and 3 months after treatment, while that of the half-dose PDT group improved like the SMTL group. There were no significant differences between the SMTL and the PDT group at 1, 2, and 3 months ( P = 0.723 ; 0.139; 0.896). The CRT for the SMTL group decreased at 1, 2, and 3 months after treatment, while that of the half-dose PDT group changed like the SMTL group. However, there were significant differences between the SMTL group and the PDT group at 1and 3 months ( P = 0.010 ; 0.009). 13/69 (18.84%) and 9/79 (11.39%) patients underwent treatment at least twice in the SMTL and half-dose PDT group, respectively, and achieved resolution of SRF after treatment. The results of subgroups analysis showed no significant differences between the logMAR BCVA of the SMTL and PDT group which were divided into parafoveal and subfoveal leakage groups after treatment, but significant difference in CRT between subgroups can be found after treatment at 1and 3 months ( P = 0.003 ; 0.04). Conclusions. The SMTL can be an effective candidate for the treatment of persistent cCSC where leakage occurred at parafoveal or subfoveal and improvement of logMAR BCVA, but half-dose PDT has been more effective for resolution of SRF.

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“…He was diagnosed with type 1 IMT and received IVTA, but the treatment was ineffective. Thus, we administered 577 nm SMYL (Supra Scan, Quantel Medical, Cedex, France) around the juxtafoveal telangiectatic area with the following settings: 120-μm spot diameter, 20-ms duration, 15% duty cycle, 3 × 3 matrix pattern (0.5 widths), and low power, ranging from 200 to 400 mW with monthly increases in 100 mW increments, based on the response to treatment [4]. We performed a SMYL (200 and 300 mW) session for 2 months (for a total of 2 treatment sessions).…”

Section: Subthreshold Micropulse Yellow Laser (577 Nm) For Idiopathicmentioning

confidence: 99%

Subthreshold Micropulse Yellow Laser (577 nm) for Idiopathic Macular Telangiectasia Type 1 Resistant to Intravitreal Injection

Kang

Park

2020

Korean J Ophthalmol

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Short-duration multiple-session subthreshold micropulse yellow laser (577 nm) for chronic central serous chorioretinopathy: results at 3 years

Cited by 18 publications

References 29 publications

Multiple-Session Subthreshold Micropulse Laser Therapy for Exudative Perifoveal Vascular Anomalous Complex: A Case Report

Multiple-Session Subthreshold Micropulse Laser Therapy for Exudative Perifoveal Vascular Anomalous Complex: A Case Report

Subthreshold Micropulse Treatment Laser versus Half-Dose Photo Dynamic Therapy for the Chronic Central Serous Chorioretinopathy with Parafoveal or Subfoveal Leakage STML versus PDT for Treatment of Chronic CSC

Subthreshold Micropulse Yellow Laser (577 nm) for Idiopathic Macular Telangiectasia Type 1 Resistant to Intravitreal Injection

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