Short-Term Experience With a New Absorbable Composite Cage (β-Tricalcium Phosphate–Polylactic Acid) in Patients After Stand-Alone Anterior Cervical Discectomy and Fusion

Brenke, Christopher; Kindling, Stephanie; Scharf, Johann; Schmieder, Kirsten; Barth, Martin

doi:10.1097/brs.0b013e31828d65bb

Cited by 13 publications

(9 citation statements)

References 17 publications

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“…[19][20][21][22][23][24] Issues concern a low primary stability with development of cracks and some foreign body reactions with infl ammatory signs, leading to widespread skepticism of the value of bioabsorbable implants and limited use in clinical practice. [19][20][21][22][23][24] Issues concern a low primary stability with development of cracks and some foreign body reactions with infl ammatory signs, leading to widespread skepticism of the value of bioabsorbable implants and limited use in clinical practice.…”

mentioning

confidence: 99%

Bioabsorbable Interbody Magnesium-Polymer Cage

Daentzer

Willbold

Kalla³

et al. 2014

Spine

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mentioning

confidence: 99%

Bioabsorbable Interbody Magnesium-Polymer Cage

Daentzer

Willbold

Kalla³

et al. 2014

Spine

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“…In addition, complete postoperative absorption allows improved radiological assessment. However, these benefits are still theoretical, with studies showing high levels of stand-alone cage dislocation requiring revision surgeries [ 65 ].…”

Section: Discussionmentioning

confidence: 99%

The design evolution of interbody cages in anterior cervical discectomy and fusion: a systematic review

Chong

Pelletier²,

Mobbs

et al. 2015

BMC Musculoskelet Disord

127

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BackgroundAnterior cervical discectomy with fusion is a common surgical procedure for patients experiencing pain and/or neurological deficits due to cervical spondylosis. Although iliac crest bone graft remains the gold standard today, the associated morbidity has inspired the search for alternatives, including allograft, synthetic and factor/cell-based grafts; and has further led to a focus on cage fusion technology. Compared to their graft counterparts, cage interbody implants have enhanced biomechanical properties, with designs constantly improving to maximise biocompatibility and osseointegration. We present a systematic review examining the historical progress of implant designs and performance, as well as an update on the currently available designs, and the potential future of cervical interbody implants.MethodsWe performed a systematic review using the keywords “cervical fusion implant design”, with no limits on year of publication. Databases used were PubMed, Medline, Embase and Cochrane. In addition, the search was extended to the reference lists of selected articles.Results180 articles were reviewed and 64 articles were eligible for inclusion. Exclusion criteria were based around study design, implant information and patient cohorts. The evolution of cage implant design has been shaped by improved understanding of ideal anatomy, progress in materials research and continuing experimentation of structural design. Originally, designs varied primarily in their choice of structure, however long-term studies have displayed the overall advantages of non-threaded, wedge shaped cages in complementing healthy anatomical profiles, and thus focus has shifted to refining material utilisation and streamlining anterior fixation.ConclusionsEvolution of design has been dramatic over the past decades; however an ideal cage design has yet to be realised. Current research is focusing on the promotion of osseointegration through bioactiviation of surface materials, as well as streamlining anterior fixation with the introduction of integrated screws and zero profile designs. Future designs will benefit from a combination of these advances in order to achieve ideal disc heights, cervical alignments and fusions.Electronic supplementary materialThe online version of this article (doi:10.1186/s12891-015-0546-x) contains supplementary material, which is available to authorized users.

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“…Although they were mostly mild like transient dysphagia or dysphonia, severe complications like vertebral artery injuries have been described [16]. Very recently, cases of implant extrusion in ACDF and also in arthroplasty have been published [17,18]. The development of adjacent segment disease as a consequence of ACDF has been discussed controversially [19,20,21] but still remains a concern.…”

Section: Discussionmentioning

confidence: 99%

Retrospective Evaluation of Efficiency and Safety of an Anterior Percutaneous Approach for Cervical Discectomy

Schubert¹,

Merk²

2014

Asian Spine J

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Study DesignRetrospective case series.PurposeThe purpose of the study was to evaluate the efficiency and complication rate of a percutaneous anterior approach to herniated cervical disks with or without concomitant foraminal stenosis and/or spondylosis.Overview of LiteratureRecent publications reflect that minimally invasive procedures gain in importance in patients and spine surgeons as they are generally associated with less tissue damage and shorter recovery times. However, for anterior percutaneous cervical discectomy, very little data is available for relevant patient populations.MethodsCharts from patients with herniated cervical disc confirmed by magnetic resonance imaging, mainly radicular symptoms and irresponsive to conservative treatment who underwent anterior percutaneous discectomy were evaluated retrospectively. All patients were asked to return questionnaires that included visual analogue scores (VAS), MacNab score as well as subjective satisfaction data 2 years after surgery.ResultsNinety-five patients were included. There were no neurological or vascular complications; only one patient suffered from transient hoarseness. During the two years after surgery, 9 patients underwent reoperation. 90.5% of the patients returned the questionnaire at 2 years' follow-up. 87.7% of them reported excellent or good outcome, 11.1% rated results as fair and 1.2% as unsatisfactory. On average, arm and neck pain improved significantly by 6.1 points and 5.8 points respectively on a ten point VAS. 94.5% stated that they would choose the same procedure again.ConclusionsThis procedure has proved a safe and sufficient option for symptomatic cervical disk herniations with or without concomitant spondylosis and/or foraminal stenosis.

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Short-Term Experience With a New Absorbable Composite Cage (β-Tricalcium Phosphate–Polylactic Acid) in Patients After Stand-Alone Anterior Cervical Discectomy and Fusion

Abstract: 2.

Cited by 13 publications

References 17 publications

Bioabsorbable Interbody Magnesium-Polymer Cage

Bioabsorbable Interbody Magnesium-Polymer Cage

The design evolution of interbody cages in anterior cervical discectomy and fusion: a systematic review

Retrospective Evaluation of Efficiency and Safety of an Anterior Percutaneous Approach for Cervical Discectomy

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