Short-term memory effects in the phototactic behavior of microalgae

Laroussi, Taha; Jarrahi, Mojtaba; Amselem, Gabriel

doi:10.1039/d3sm01628e

Cited by 2 publications

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Light‐Driven Green‐Fabricated Artificial Intelligence‐Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer

Hsiao,

Lin,

Liu

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

Combination therapy based on precise phototherapies combined with immune modulation provides successful antitumor effects. In this study, a combination therapy is designed based on phototactic, photosynthetic, and phototherapeutic Chlamydomonas Reinhardtii (CHL)‐glycol chitosan (GCS)‐polypyrrole (PPy) nanoparticle (NP)‐enhanced immunity combined with the tumor microenvironment turnover of cytotoxic T cells and M1/M2 macrophages, which is based on photothermal GCS‐PPy NPs decorated onto the phototactic and photosynthetic CHL. Phototherapy based on CHL‐GCS‐PPy NPs alleviates hypoxia and modulates the tumor immune microenvironment, which induces tumor cell death. In particular, the precise antitumor immune response and potent immune memory induced by combining self‐navigated phototherapies significantly alleviate the progression of bladder cancer in C57BL/6 mice and effectively inhibit bladder tumor growth. Furthermore, they also potentially prevent tumor recurrence, which provides a promising therapeutic strategy for clinical tumor therapy.

show abstract

Light‐Driven Green‐Fabricated Artificial Intelligence‐Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer

Hsiao,

Lin,

Liu

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

show abstract

Adaptation-induced oscillatory phototaxis and emergence of ordered density bands in the microswimmerChlamydomonas reinhardtii

Wang,

Tsang

2024

Preprint

View full text Add to dashboard Cite

Biological microswimmers exhibit versatile taxis behaviors and switch between multiple behavioral states to navigate the environment and search for physiologically favorable regions. Here, we report a striking oscillatory phototaxis observed inChlamydomonas reinhardtii, where cells swim back-and-forth under a constant, unidirectional light stimulus due to alternation between positive and negative phototaxis. This oscillatory phototaxis at the individual cellular level further leads to the emergence of a highly ordered, propagating band structure formed by high densityChlamydomonascells collectively. We experimentally verify a unified phototaxis mechanism that couples light detection, light adaptation, flagella dynamics and cell reorientation, showing that transition between phototaxis modes is achieved by switching of flagella waveforms and modulation of flagella phase difference. Oscillatory phototaxis emerges as a semi-stable state in an overlapping light intensity regime for positive and negative phototaxis, where adaptation shifts the light intensity thresholds over times. This adaptation mechanism over multiple time scales enables phototactic microswimmers to effectively expand the survival range of light intensity and provide collective photoprotection for the colonies through the formation of dynamic band structures with high density.

show abstract

Short-term memory effects in the phototactic behavior of microalgae

Abstract: Phototaxis, the directed motion in response to a light stimulus, is crucial for motile microorganisms that rely on photosynthesis, such as the unicellular microalga Chlamydomonas reinhardtii. It is well known...

Cited by 2 publications

References 41 publications

Light‐Driven Green‐Fabricated Artificial Intelligence‐Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer

Light‐Driven Green‐Fabricated Artificial Intelligence‐Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer

Adaptation-induced oscillatory phototaxis and emergence of ordered density bands in the microswimmerChlamydomonas reinhardtii

Contact Info

Product

Resources

About