Short term outcomes associated with patients requiring blood transfusion following elective laminectomy and fusion for lumbar stenosis: A propensity-matched analysis

Darveau, Spencer C.; Pertsch, Nathan J.; Toms, Steven; Weil, Robert J.

doi:10.1016/j.jocn.2021.05.061

Cited by 6 publications

(15 citation statements)

References 44 publications

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“…4,5 Associated with reactive, infectious, and autoimmune risks, 6 BT can complicate postoperative prognoses across various surgical subspecialties and is resource-intensive. [7][8][9][10] While BT is often based on a perceived clinical need, some patient-level characteristics also contribute to increased risk of BT, including age, gender, weight, American Society of Anesthesiology (ASA) physical status, and preoperative anemia. 11,12 Evidence from studies conducted on animals undergoing thyroidectomy indicates poor survival rates among BT recipients.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, existing literature has also evaluated BT as an independent risk factor for postoperative complications 4,5 . Associated with reactive, infectious, and autoimmune risks, 6 BT can complicate postoperative prognoses across various surgical subspecialties and is resource‐intensive 7–10 . While BT is often based on a perceived clinical need, some patient‐level characteristics also contribute to increased risk of BT, including age, gender, weight, American Society of Anesthesiology (ASA) physical status, and preoperative anemia 11,12 …”

Section: Introductionmentioning

confidence: 99%

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A Comprehensive Assessment of Blood Transfusions in Elective Thyroidectomy Based on 180,483 Patients

et al. 2022

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Objectives To assess the incidence, risk factors, and complications of blood transfusions (BTs) in elective thyroidectomy patients. Methods A retrospective cohort study was conducted using the American College of Surgeons National Surgical Quality Improvement Program. Adult patients who underwent elective thyroidectomy from 2005 to 2019 were divided into two cohorts based on whether they received BT or not. Multivariable binary logistic regression models were used to identify risk factors of BT and its impact on postoperative complications. Results Of 180,483 patients, 0.13% received BT. Risk factors for BT included underweight body mass index (BMI) (adjusted odds ratio [OR] 3.179, 95% confidence interval [CI] 1.444–6.996), bleeding disorders (OR 2.121, 95% CI 1.149–3.913), anemia (OR 4.730, 95% CI 3.472–6.445), preoperative transfusion (OR 7.230, 95% CI 1.454–35.946), American Society of Anesthesiology physical statuses 3–5 (OR 3.103, 95% CI 2.143–4.492), operative time >150 min (OR 4.390, 95% CI 1.996–9.654), and inpatient thyroidectomy (OR 5.791, 95% CI 3.816–8.787). In addition, transfusion was independently associated with any postoperative complication, non‐infectious, cardiac, pulmonary, renal, vascular, or infectious complications, surgical site infection, sepsis, septic shock, wound disruption, pneumonia, unplanned reoperation, prolonged length of stay, and mortality. Conclusion Recognition of risk factors of BT is imperative to identify at‐risk patients and reduce transfusions by controlling modifiable risk factors such as anemia, operative time, and BMI. In cases where transfusions are still indicated, surgeons should optimize care to prevent or adequately manage transfusion‐associated complications. Level of Evidence 3 Laryngoscope, 132:2078–2084, 2022

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Comprehensive Assessment of Blood Transfusions in Elective Thyroidectomy Based on 180,483 Patients

et al. 2022

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“…A total of 23 studies 7 - 9 , 14 , 15 , 19 , 20 , 23 , 26 , 28 - 33 , 35 , 38 - 43 , 45 were defined as having a moderate risk of bias and 13 13 , 16 - 18 , 21 , 22 , 24 , 25 , 27 , 34 , 36 , 37 , 44 were deemed to have a high risk of bias.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 36 studies 7-9,13-45 were included (Table 1). Of these, 26 7,13-18,20-22,24,25,27,28,33-40,42-45 were retrospective cohort studies, 1 23 was a prospective cohort study and 9 8,9,19,26,29-32,41 were case-control studies. Among them, 20 7,9,15-17,23,25,26,29,32-36,38-40,42,44,45 included patients from the NSQIP database, 2 from State Inpatient Databases (SID) 13,28 , 3 from Nationwide Readmissions Database (NRD) 8,18,41 , 4 from the Medicare database 20,24,37,43 , 2 from the Quality Outcomes Database (QOD) 21,22 , and 3 from institutional database 14,19,31 .…”

Section: Resultsmentioning

confidence: 99%

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Risk Factors for 30-day Unplanned Readmission following Surgery for Lumbar Degenerative Diseases: A Systematic Review

Chen

Chang

Wong

et al. 2022

Global Spine Journal

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Study design Systematic review. Objectives Surgical procedures for lumbar degenerative diseases (LDD), which have emerged in the 21-century, are commonly practiced worldwide. Regarding financial burdens and health costs, readmissions within 30days following surgery are inconvenient. We performed a systematic review to integrate real-world evidence and report the current risk factors associated with 30-day readmission following surgery for LDD. Methods The Cochrane Library, Embase, and Medline electronic databases were searched from inception to April 2022 to identify relevant studies reporting risk factors for 30-day readmission following surgery for LDD. Results Thirty-six studies were included in the review. Potential risk factors were identified in the included studies that reported multivariate analysis results, including age, race, obesity, higher American Society of Anesthesiologists score, anemia, bleeding disorder, chronic pulmonary disease, heart failure, dependent status, depression, diabetes, frailty, malnutrition, chronic steroid use, surgeries with anterior approach, multilevel spinal surgeries, perioperative transfusion, presence of postoperative complications, prolonged operative time, and prolonged length of stay. Conclusions There are several potential perioperative risk factors associated with unplanned readmission following surgery for LDD. Preoperatively identifying patients that are at increased risk of readmission is critical for achieving the best possible outcomes.

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The severity of preoperative anemia escalates risk of poor short-term outcomes after lumbar spine fusion

et al. 2023

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Short term outcomes associated with patients requiring blood transfusion following elective laminectomy and fusion for lumbar stenosis: A propensity-matched analysis

Cited by 6 publications

References 44 publications

A Comprehensive Assessment of Blood Transfusions in Elective Thyroidectomy Based on 180,483 Patients

A Comprehensive Assessment of Blood Transfusions in Elective Thyroidectomy Based on 180,483 Patients

Risk Factors for 30-day Unplanned Readmission following Surgery for Lumbar Degenerative Diseases: A Systematic Review

The severity of preoperative anemia escalates risk of poor short-term outcomes after lumbar spine fusion

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