Sıçanların Meme Dokusunda Gebelik, Laktasyon ve İnvolusyon Periyodları Süresince Ghrelin, Obestatin ve Leptin Dağılımı

Saruhan, Berna Güney; Sağsöz, Hakan; Topaloğlu, Uğur

doi:10.47027/duvetfd.828804

Cited by 1 publication

(1 citation statement)

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“…Semi-quantitative evaluation. Tissue immunoreactions for Dlx-5 and TLX1 were evaluated with a semi-quantitative scoring method (Saruhan et al, 2020), as either negative (-), weak (+), moderate (++) or strong (+++). This evaluation was made independently by two senior histologists (UT and MEA), based on average values.…”

Section: Methodsmentioning

confidence: 99%

Expression of the Homeobox Proteins Dlx-5 and TLX1 During the Development of Cat Testis

Topaloğlu

Akbalık

2022

Int. J. Morphol.

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Recent studies have shown that homeobox proteins play an important role in the formation and development of tissues and organs in the embryonic period. In our study, the distribution of Dlx-5 and TLX proteins, which are members of the homeobox family, in the testis, epididymis and ductus deferens ducts of some cat breeds were investigated. For this purpose, in the study, 18 testes younger than six months (immature) and older than one year (mature) were examined under a light microscope using an immunohistochemical method (indirect streptavidin-biotin complex). While it was determined that Dlx-5 and TLX1 proteins were expressed at varying levels in cells in immature and mature cat testicles, epithelial cells of ductus epididymis and ductus deferens, and smooth muscle cells of ductus deferens, no differences were observed between cat breeds. Dlx-5 immunoreactivity was more intense in the testes, epididymis and deferens ducts of immature and mature compared to TLX1. These results suggested that both proteins play important roles in the development of male feline genital organs and in the secretion and differentiation of cells, and also further observation of Dlx-5 expression suggested that this protein may be more effective than TLX1 in testicular development and physiological processes.

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Section: Methodsmentioning

confidence: 99%