Significant sex differences in the correlation of electrocardiographic exercise testing and coronary arteriograms

Effects of Pravastatin on Exercise Electrocardiography Test Performance and Cardiovascular Mortality and Morbidity in Patients With Hypercholesterolemia

“…However, significant gender differences in the correlation between exercise testing and coronary arteriograms have been reported. 21 The incidence of true positive exercise test results in men was 89%, in contrast to 33% in women. More women than men were enrolled in the present study, which may have affected the results.…”

Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic Heart Disease

“…The sensitivity and specificity for the diagnosis of obstructive CAD in women range from 31% to 71% and from 66% to 86%, respectively. [77][78][79][80][81][82][83][84] In a meta-analysis of 19 exercise ECG studies, the mean sensitivity and specificity, respectively, were 61% and 70% among women and 72% and 77% among 1977 men. 80 In a recent Agency for Healthcare Research and Quality (AHRQ) meta-analysis, 29 studies that included 3392 women were synthesized, with a reported diagnostic sensitivity and specificity, respectively, of 62% (95% confidence interval [CI], 55%-68%) and 68% (95% CI, 63%-73%) for detection of obstructive CAD.…”

Dobutamine stress echocardiography in the diagnosis of coronary artery disease in women with chest pain: Comparison with different noninvasive tests

“…Second, in women with conclusive tests and an intermediate probability of CAD like in our population, abnormal test results are likely to be false positive. 24,25 According to these results, EX should be discouraged as a screening test in women suspected of having ischemic chest pain.…”