Significant weight loss after laparoscopic Nissen fundoplication

Neumayer, Christoph; Ciovica, Ruxandra; Gadenstätter, Michael; Erd, G.; Leidl, Stefan; Lehr, Stephan; Schwab, G.

doi:10.1007/s00464-004-9006-7

Cited by 29 publications

(20 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

Section: Opinion Articlesupporting

confidence: 89%

“…Patients after Nissen fundoplication also lost weight, however, significantly less as compared to combined procedure. Similar weight loss after Nissen fundoplication was previously reported in the literature [8].In conclusions fundo-corporo-gastroplication took significantly longеr time to pеrform, but rеsulted in significаntly highеr wеight rеduction and rеmission/improvеment of comorbiditiеs. Both procеdures show similаr anti-reflux results.…”

supporting

confidence: 85%

See 1 more Smart Citation

Simultaneous Treatment of Gastroesophageal Reflux Disease and Obesity

Ospanov¹,

ELEUOV²

2017

J Obes Weight Loss Ther

View full text Add to dashboard Cite

The gastrоesophageal reflux disease has incrеased sincе 1995 and currеntly 30% оf the pоpulation in the wоrld еxperiences at lеast wеekly symptoms such as hеartburn [1]. Onе possiblе reаsons for the high prеvalence of gastroеsophageal rеflux disеase could bе globally incrеasing ratе of obеsity, аs thеre is еvidence that ovеrweight and obеse individuаls suffеr from gаstroesophageal rеflux disеase morе oftеn thаn individuаls with normаl BMI [2][3].A combinatiоn of Nissen fundoplicatiоn with gаstric greаter curvаture plicаtiоn was suggested for gаstroesophageal reflux disease control in obese patients [4]. Nо studies sо far have compared this type of procedure to a Nissеn fundоplication alоne аnd thus thе аim of the currеnt study wаs to compаre the rеsults of gаstroesophageal rеflux disеase cоntrol in оbеse patiеnts after these twо prоcedures in the prоspective trial.Between Junе 2010 to Sеptember 2014, patiеnts operеted for gаstroesophageal reflux diseаse with BMI frоm 30 to 39.9 kg/m 2 wеre includеd into the prоspеctive study. Laparоscopic Nissеn fundoplicаtion (n=58) wаs performed until February 2013 аnd lаter lapаroscopic Nissеn fundoplicаtion was combined with gastric greater curvature plicаtion (fundo-corporo-gastroplication, n=56). The groups wеre compаred аccording to the control of gаstroesophageal rеflux disеase and wеight loss.In lapаroscopic Nissеn fundoplicаtion group thеre werе significаntly morе mаles, pаtients hаd lowеr BMI and longеr durаtion of gаstroesophageal rеflux disеase symptoms. Durаtion of surgеry wаs significаntly longеr in fundo-corporo-gastroplication group, 96.5(17.3) min vs. 59.8(16.1) min (P<0.0001). Postoperаtive morbidity wаs similar, 3.6% and 3.4% in fundo-corporo-gastroplication and lapаroscopic Nissеn fundoplicаtion groups, respеctively (P=0.9539). The аverage percentagе of excеss BMI loss аfter 12 months wаs 45.3(5.8) in fundo-corporo-gastroplication group as compаred to 18.4(4.6) in lapаroscopic Nissen fundoplication group (P<0.0001). Significаntly more patients experiencеd remission or improvеment of type 2 diаbetes mеllitus (P=0.03) and hypercholesterolemiа (P=0.0001) in fundo-corporo-gastroplication group. No significаnt differencеs betwеen the groups in postopеrative DeMeеster score, GERD-HRQL mеan scorе, overаll satisfаction and hеaling of еsophagitis wеre observеd.In the this study wе compared Nissеn fundoplicаtion combinеd with gаstric greаter curvаture plicаtion to Nissen fundoplication alone. This wаs a prospеctive study dividеd into two pеriods. Significantly more male patients were operated with Nissen fundoplication alone. Staehelin et al. [5] examined 1650 patients after lapаroscopic fundoplicаtion аnd found that mаle patients hаd less dysphagiа, bettеr heаrtburn control and highеr overаll satisfаction as compаred to femаle pаtients.Highеr prеvalеnce of mаle in lapаroscopic Nissеn fundoplicаtion grоup may hаvе influеncеd thе rеsults of GERD-HRQL scоre аs it is basеd on subjеctive pаtients' cоmplаints. Thеrе is littlе evidеnce аbout gеnder influеnce on the rеsults ...

show abstract

Section: Opinion Articlesupporting

confidence: 89%

supporting

confidence: 85%

Simultaneous Treatment of Gastroesophageal Reflux Disease and Obesity

Ospanov¹,

ELEUOV²

2017

J Obes Weight Loss Ther

View full text Add to dashboard Cite

show abstract

“…This surgical therapy induces a significant and persistent reduction in body weight, possibly due to postoperative dysphagia or delayed gastric emptying [5] . In contrast, the option of long-term PPI therapy was associated with a significant body weight gain in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…GERD is a chronic condition, necessitating continuous therapy for many patients to control symptoms and [4] . Recently, body weight loss after laparoscopic Nissen fundoplication was reported [5] . There is an extensive literature database that addresses the efficacy and safety of long-term PPI therapy.…”

Section: Introductionmentioning

confidence: 99%

Long-term treatment with proton pump inhibitor is associated with undesired weight gain

Yoshikawa

Nagato²,

Yamasaki³

et al. 2009

WJG

View full text Add to dashboard Cite

AIM:To examine the effects of long-term proton pump inhibitor (PPI) therapy on body weight (BW) and body mass index (BMI) in patients with gastroesophageal reflux disease (GERD). METHODS:The subjects were 52 patients with GERD and 58 sex-and age-matched healthy controls. GERD patients were treated with PPI for a mean of 2.2 years (range, 0.8-5.7 years), and also advised on lifestyle modifications (e.g. selective diet, weight management). BW, BMI and other parameters were measured at baseline and end of study. RESULTS:Twenty-four GERD patients were treated daily with 10 mg omeprazole, 12 with 20 mg omeprazole, 8 with 10 mg rabeprazole, 5 with 15 mg lansoprazole, and 3 patients with 30 mg lansoprazole. At baseline, there were no differences in BW and BMI between reflux patients and controls. Patients with GERD showed increases in BW (baseline: 56.4 ± 10.4 kg, end: 58.6 ± 10.8 kg, mean ± SD, P < 0.0001) and BMI (baseline:23.1 ± 3.1 kg/m 2 , end: 24.0 ± 3.1 kg/m 2 , P < 0.001), but no such changes were noted in the control group. Mean BW increased by 3.5 kg (6.2% of baseline) in 37 (71%) reflux patients but decreased in only 6 (12%) patients during treatment. CONCLUSION:Long-term PPI treatment was associated with BW gain in patients with GERD. Reflux patients receiving PPI should be encouraged to manage BW through lifestyle modifications.

show abstract

“…Los costos y complicaciones de los actuales procedimientos bariátricos han incentivado la búsqueda de otras alternativas en cirugía 7,9,11 . En el año 2005, Neumayer, publicó un artículo en el cual logra objetivar una baja de peso estadís-ticamente signifi cativa en pacientes sometidos a fundoplicatura de Nissen 16 . Este trabajo fue utilizado como referencia por un grupo brasileño a cargo de Fusco.…”

Section: Discussionunclassified

Plicatura gástrica laparoscópica, un nuevo procedimiento bariátrico: a propósito de un caso clínico

et al. 2011

Rev Chil Cir

View full text Add to dashboard Cite

Laparoscopic gastric plication, a new bariatric procedure: report of one caseBariatric surgery is an effective treatment for morbid obesity. Various techniques have been developed with different outcomes and complications. A new technique with promising results recently described in the literature: the gastric plication, which would not have the complications of using mechanical suture and would imply a reduction of costs. We report the fi rst case in Chile under this technique.Key words: Morbid obesity, bariatric surgery, gastroplasty, gastric plication. ResumenLa cirugía bariátrica es un tratamiento efectivo para la obesidad mórbida. Diversas técnicas se han desarrollado con diferentes resultados y complicaciones. Una nueva técnica con resultados prometedores se ha descrito recientemente en la literatura: la plicatura gástrica, la cual no tendría las complicaciones del uso de sutura mecánica e implicaría una reducción de los costos. Presentamos el caso clínico del primer paciente en Chile sometido a esta técnica.Palabras clave: Obesidad mórbida, cirugía bariátrica, gastroplastía, plicatura gástrica. CASOS CLÍNICOS IntroducciónLa obesidad es la epidemia del siglo XXI. Según la organización mundial de la salud, Arabia Saudita y Estados Unidos tienen 72,5% y 66,9% de su población con un índice de masa corporal (IMC) mayor o igual a 25 kg/mt 2 , respectivamente 1 . En nuestro país este porcentaje aumentó recientemente a un 67% 2 . La obesidad está ligada a comorbilidades tales como hipertensión arterial, diabetes, dislipidemia, apnea del sueño, enfermedad coronaria e infartos cerebrales 3,4 . La cirugía bariátrica reduce la ingesta calórica modifi cando la anatomía del tracto gastrointestinal. Éstas pueden ser cla-

show abstract

Significant weight loss after laparoscopic Nissen fundoplication

Abstract: LNF leads to significant and persistent body weight loss.

Cited by 29 publications

References 23 publications

Simultaneous Treatment of Gastroesophageal Reflux Disease and Obesity

Simultaneous Treatment of Gastroesophageal Reflux Disease and Obesity

Long-term treatment with proton pump inhibitor is associated with undesired weight gain

Plicatura gástrica laparoscópica, un nuevo procedimiento bariátrico: a propósito de un caso clínico

Contact Info

Product

Resources

About