Significantly Accelerated Direct Electron‐Transfer Kinetics of Hemoglobin in a C₆₀‐MWCNT Nanocomposite Film

Abstract

The direct electrochemistry of hemoglobin (Hb) was studied in a novel all-carbon nanocomposite film of C(60)-MWCNT (MWCNT=multiple-walled carbon nanotube) and compared with that in bare MWCNT film. The heterogeneous electron-transfer rate constant k(s) of Hb/C(60)-MWCNT was determined to be 0.39 s(-1), which is more than one order of magnitude greater than that of Hb/MWCNT (0.03 s(-1)). The significantly accelerated electron-transfer kinetics are attributed to the mediator role played by C(60), which is finely dispersed on the MWCNT surfaces. The excellent stability of Hb/C(60)-MWCNT was established and its potential application towards the electrocatalytic reduction of O(2) was demonstrated.

Highly Selective and Sensitive Detection of Dopamine in the Presence of Excessive Ascorbic Acid Using Electrodes Modified with C60‐Functionalized Multiwalled Carbon Nanotube Films

“…As demonstrated previously [36,37], the electrochemically prepared C 60 -MWCNTs composite film presents very stable electrochemical behavior. Before presenting the electrochemical details, it is of interest to examine the nanoscale morphology of the C 60 -MWCNTs composite film.…”

“…The C 60 -MWCNTs films were found to be more effective in facilitating the direct electron transfer of hemoglobin (Hb) than MWCNTs films. More specific, the heterogeneous electron transfer rate constant k s of Hb on C 60 -MWCNTs composite film is almost an order of magnitude larger than that on MWCNTs film [37].…”

Electrochemistry of myoglobin on graphene–SnO2 nanocomposite modified electrode and its electrocatalysis

“…It is well known that k s value reflects the local microenvironment of protein immobilized on the electrode. This k s value is higher than the values of Mb when immobilized on C 60 -multiwalled CNT based electrode (0.39 s À1 , Zhang et al, 2006), Ag-CNTs modified GCE (0.41 s À1 , Liu and Hu, 2009), NiO nanoparticle modified GCE (0.34 s À1 , Moghaddam et al, 2008), Co nanoparticle modified CILE (0.588 s À1 , Sun et al, 2009) and GO-IL modified CILE (0.584 s À1 , , indicating the electron transfer of Mb was facilitated on GR-SnO 2 nanocomposite modified electrode.…”

Carbon Nanotube-Based Thin Films: Synthesis and Properties

“…Using the above method, hemoglobin (Hb) was embedded into C 60 -CNT film. [124] Experimental results demonstrated that C 60 -CNT films can facilitate the direct electron transfer of Hb much more effectively than bare CNT films. This is attributed to the faster electron-transfer kinetics on the C 60 -CNT film from the roles of electron mediator and protein docking site played by C 60 , which is finely dispersed on the MWNT surfaces.…”