Silanized carbon dot-based thermo-sensitive molecularly imprinted fluorescent sensor for bovine hemoglobin detection

Application progress of magnetic molecularly imprinted polymers chemical sensors in the detection of biomarkers

“…Up to now, MMIPs-FL has been used more in the detection of bovine hemoglobin (BHb), a biomarker of anemia. 108 Zhao et al 109 constructed a silylated carbon point thermosensitive molecularly imprinted fluorescent sensor to detect BHb using the SMIT. The silylated carbon dots enhance the fluorescence signal and increase the imprinting depth, which improves the sensor's performance.…”

Preparation of carbon-based metal organic framework-modified molecularly imprinted polymers for selective recognition of bovine hemoglobin in biological samples

“…In addition, the selectivity coefficient (SC) is another important factor for selectivity evaluation. The formula is shown in eqn (3).…”

“…Bovine hemoglobin (BHb) has a high similarity with Hb, with around 90% match of amino acid sequence, thus acting as an impeccable substitute of Hb protein. 3,4 Accurate monitoring of a high-quality biological macromolecule like BHb is challenging owing to its complex structure and uncontrollable stability, which emphasizes the need for the development of an efficient method for the separation and enrichment of BHb in complex biological samples. 5 Currently, a plethora of enrichment strategies have been developed for the separation of highly-abundant proteins, including lectin affinity, hydrophilic, and electrostatic interactions, etc.…”

Adaptive Nanoparticle‐Polymer Complexes as Optical Elements: Design and Application in Nanophotonics and Nanomedicine

“…[ 54 ] In another work, silanized carbon dots coated by the molecularly imprinted polymer were used as the fluorescent thermo‐sensor for bovine hemoglobin detection. [ 55 ]…”