Silver(I) Complexes with Mefenamic Acid and Nitrogen Heterocyclic Ligands: Synthesis, Characterization, and Biological Evaluation

Zhang, Lu-Lin; Huang, Xiang; Azam, Mohammad; Yuan, Hua-Xin; Ma, Feng-Jie; Cheng, Yuan-Zheng; Zhang, Li-Ping; Sun, Di

doi:10.1021/acs.inorgchem.4c01766

Inorg. Chem.

2024

DOI: 10.1021/acs.inorgchem.4c01766

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Silver(I) Complexes with Mefenamic Acid and Nitrogen Heterocyclic Ligands: Synthesis, Characterization, and Biological Evaluation

Lu-Lin Zhang,

Xiang Huang,

Mohammad Azam

et al.

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2024

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Cited by 2 publications

References 90 publications

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A hexanuclear cerium(IV) complex with the non–steroidal anti–inflammatory drug mefenamic acid

Perontsis,

Chrysoulidis,

Hatzidimitriou

et al. 2024

Journal of Coordination Chemistry

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A hexanuclear cerium(IV) complex with the non–steroidal anti–inflammatory drug mefenamic acid

Perontsis,

Chrysoulidis,

Hatzidimitriou

et al. 2024

Journal of Coordination Chemistry

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Manganese(II) Complexes with Non-Steroidal Anti-Inflammatory Drugs: Structure and Biological Activity

Dimiza,

Hatzidimitriou,

Psomas

2024

IJMS

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Nine manganese(II) complexes with a series of non-steroidal anti-inflammatory drugs (namely sodium diclofenac, diflunisal, flufenamic acid, sodium meclofenamate, mefenamic acid, and tolfenamic acid) were prepared in the presence of diverse nitrogen donors, i.e., pyridine, 1,10–phenanthroline, 2,2′–bipyridine and neocuproine, as co-ligands and were characterized with spectroscopic techniques and single-crystal X-ray crystallography. The biological profile of the resultant complexes was investigated regarding their antioxidant potency and their interaction with DNA and serum albumins. The complexes interact with calf–thymus DNA in an intercalative mode and bind tightly and reversibly to human and bovine serum albumins studied. In order to assess the antioxidant activity of the Mn(II) complexes, their ability to scavenge 2,2′–azinobis(3–ethylbenzothiazoline–6–sulfonic acid) free radicals was monitored.

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Silver(I) Complexes with Mefenamic Acid and Nitrogen Heterocyclic Ligands: Synthesis, Characterization, and Biological Evaluation

Cited by 2 publications

References 90 publications

A hexanuclear cerium(IV) complex with the non–steroidal anti–inflammatory drug mefenamic acid

A hexanuclear cerium(IV) complex with the non–steroidal anti–inflammatory drug mefenamic acid

Manganese(II) Complexes with Non-Steroidal Anti-Inflammatory Drugs: Structure and Biological Activity

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