Silver oxide decorated urchin-like microporous organic polymer composites as versatile antibacterial organic coating materials

Zhang, Yu; Tang, Yunxin; Liao, Qian; Qian, Yiduo; Zhu, Linglin; Yu, Deng-Guang; Xu, Yixin; Lu, Xiuhong; Kim, Il; Song, Wenliang

doi:10.1039/d3tb02619a

Cited by 19 publications

(5 citation statements)

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Effective, safe, and convenient cancer therapy remains one of the greatest concerns in many medical and clinical fields today ( Chen et al, 2022 ; Murugesan and Raman, 2022 ; Tang et al, 2022 ; Assi et al, 2023 ; Wang et al, 2023d ; Man et al, 2023 ; Meng et al, 2022 ). Numerous active ingredients have been demonstrated for their usefulness through laboratory experiments ( Yang et al, 2024a ; Duan et al, 2024 ; Zhang et al, 2024d ); meanwhile, new types of pharmaceutical excipients (particularly those based on polymers) are being developed continuously ( Lu et al, 2022 ; Shen et al, 2022 ; Ali et al, 2023 ; Yang et al, 2024b ; Zhang et al, 2024e ; Javadi and Mohsenzadeh, 2024 ; Riaz et al, 2024 ), and novel biosourced drug carriers such as exosomes are being considered for DDSs ( Agrawal et al, 2024 ; Guo et al, 2024 ). Combining the advantages of advanced techniques with those of traditional methods to create novel medical materials from these active ingredients and excipients is an evergreen interdisciplinary challenge for researchers.…”

Section: Discussionmentioning

confidence: 99%

Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery

Mao,

Zhou,

Yan

et al. 2024

Front. Bioeng. Biotechnol.

Self Cite

View full text Add to dashboard Cite

Combination therapy with oral administration of several active ingredients is a popular clinical treatment for cancer. However, the traditional method has poor convenience, less safety, and low efficiency for patients. The combination of traditional pharmaceutical techniques and advanced material conversion methods can provide new solutions to this issue. In this research, a new kind of hybrid film was created via coaxial electrospraying, followed by a casting process. The films were composed of Reglan and 5-fluorouracil (5-FU)-loaded cellulose acetate (CA) core-shell particles in a polyvinylpyrrolidone (PVP) film matrix. Microscopic observations of these films demonstrated a solid cross section loaded with core-shell particles. X-ray diffraction and Fourier-transform infrared tests verified that the Reglan and 5-FU loaded in the films showed amorphous states and fine compatibilities with the polymeric matrices, i.e., PVP and CA, respectively. In vitro dissolution tests indicated that the films were able to provide the desired asynchronous dual-drug delivery, fast release of Reglan, and sustained release of 5-FU. The controlled release mechanisms were shown to be an erosion mechanism for Reglan and a typical Fickian diffusion mechanism for 5-FU. The protocols reported herein pioneer a new approach for fabricating biomaterials loaded with multiple drugs, each with its own controlled release behavior, for synergistic cancer treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery

Mao,

Zhou,

Yan

et al. 2024

Front. Bioeng. Biotechnol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Both insoluble and soluble polymers are employed as catalyst supports, with the former used in heterogeneous catalysis and the latter in homogeneous catalysis . Hyper-cross-linked polystyrene can be microporous, mesoporous, or macroporous depending on the monomer precursor and functional group, achieving a layered aperture distribution can be easily controlled, and when combined with the cross-linked framework, it creates numerous transport channels suitable for particle deposition . This versatility renders it a promising carrier for metallic catalysts.…”

Section: Applicationsmentioning

confidence: 99%

Versatile Hyper-Cross-Linked Polymers Derived from Waste Polystyrene: Synthesis, Properties, and Intentional Recycling

Song,

Wen,

Wang

et al. 2024

Langmuir

Self Cite

View full text Add to dashboard Cite

Waste polystyrene contributes considerably to environmental pollution due to its persistent nature, prompting a widespread consensus on the urgent need for viable recycling solutions. Owing to the aromatic groups structure of polystyrene, hyper-cross-linked polymers can be synthesized through the Friedel−Crafts cross-linking reaction using Lewis acids as catalysts. In addition, hyper-cross-linked polystyrene and its carbonaceous counterparts can be used in several important applications, which helps in their efficient recycling. This review systematically explores methods for preparing multifunctional hypercross-linked polymers from waste polystyrene and their applications in sustainable recycling. We have comprehensively outlined various synthetic approaches for these polymers and investigated their physical and chemical properties. These multifunctional polymers not only exhibit structural flexibility but also demonstrate diversity in performance, making them suitable for various applications. Through a systematic examination of synthetic methods, we showcase the cutting-edge positions of these materials in the field of hyper-crosslinked polymers. Additionally, we provide in-depth insights into the potential applications of these hyper-cross-linked polymers in intentional recycling, highlighting their important contributions to environmental protection and sustainable development. This research provides valuable references to the fields of sustainable materials science and waste management, encouraging further exploration of innovative approaches for the utilization of discarded polystyrene.

show abstract

“…For "efficacious, safe and convenient" drug delivery, a series of drug release profiles have been developed (Riaz et al, 2024;Shi, Liu, et al, 2024;Shi, Zhang, et al, 2024;Zhang, Tang, et al, 2024;. According to the drug controlled release rate, drug release can be modified to pulsatile release (or fast release), sustained release (or extended release), biphasic release (typically a fast release followed by a sustained release), oral delayed release by a pH-sensitive polymer to resist stomach acid (Figure 4a).…”

Section: Electrospun Nanofibrous Shapes For Drug Releasementioning

confidence: 99%

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Yu,

Gong,

Zhou

et al. 2024

WIREs Nanomed Nanobiotechnol

View full text Add to dashboard Cite

The shapes of micro‐ and nano‐products have profound influences on their functional performances, which has not received sufficient attention during the past several decades. Electrohydrodynamic atomization (EHDA) techniques, mainly include electrospinning and electrospraying, are facile in manipulate their products' shapes. In this review, the shapes generated using EHDA for modifying drug release profiles are reviewed. These shapes include linear nanofibers, round micro‐/nano‐particles, and beads‐on‐a‐string hybrids. They can be further divided into different kinds of sub‐shapes, and can be explored for providing the desired pulsatile release, sustained release, biphasic release, delayed release, and pH‐sensitive release. Additionally, the shapes resulted from the organizations of electrospun nanofibers are discussed for drug delivery, and the shapes and inner structures can be considered together for developing novel drug delivery systems. In future, the shapes and the related shape–performance relationships at nanoscale, besides the size, inner structure and the related structure–performance relationships, would further play their important roles in promoting the further developments of drug delivery field.This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies

show abstract

Silver oxide decorated urchin-like microporous organic polymer composites as versatile antibacterial organic coating materials

Abstract: Microporous organic polymers (MOPs) and metal oxide hybrid composites are considered valuable coating materials because of their versatility derived from the synergistic combination of MOPs’ inherent dispersibility and the distinctive...

Cited by 19 publications

References 82 publications

Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery

Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery

Versatile Hyper-Cross-Linked Polymers Derived from Waste Polystyrene: Synthesis, Properties, and Intentional Recycling

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Contact Info

Product

Resources

About