Simian-Human Immunodeficiency Viruses and Their Impact on Non-Human Primate Models for AIDS

Pereira, Lara; Srinivasan, Priya; Smith, James M.

doi:10.5772/53556

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“…Non-human primate (NHP) models challenged with simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus (SHIV) have been used to study possible vaccine targets [18]. The SIVs are retroviruses found in non-human primates [19,20]. When SIV infects species other than their natural hosts, such as the SIV of sooty mangabeys infection of rhesus macaques, simian acquired immunodeficiency syndrome develops [19,21].…”

Section: Research Limitationsmentioning

confidence: 99%

“…The SIVs are retroviruses found in non-human primates [19,20]. When SIV infects species other than their natural hosts, such as the SIV of sooty mangabeys infection of rhesus macaques, simian acquired immunodeficiency syndrome develops [19,21]. Parts of the HIV and SIV genomes have been combined to create chimeric viruses known as SHIV.…”

Section: Research Limitationsmentioning

confidence: 99%

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