Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts

Kinoshita, Satoshi; Nishizawa, Toshihiro; Tojo, Masaya; Hirai, Yukio; Nakazato, Yoshihiro; Miyanaga, Ryoichi; Fujimoto, Ai; Inoue, Kazuaki; Ebinuma, Hirotoshi; Suzuki, Hidekazu; Kikuchi, Masahiro

doi:10.3164/jcbn.22-89

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Asymptomatic SHC does not require treatment, however symptomatic SHC needs to be treated and can be treated using different treatment modalities such as intravenous antibiotic therapy, ultrasound-guided percutaneous catheter drainage (PCD) with sclerotherapy, and surgery. [3][4][5][6][7][8][9] Following publication of the first report on endoscopic ultrasonography (EUS)-guided drainage of pancreatic pseudocysts, this technique has been widely applied in several fields [10][11][12][13] ; however, case reports describing EUS-guided drainage of symptomatic SHC are scarce. [14][15][16][17][18] In addition, there has been no comparison study of EUS-guided drainage and PCD combined with minocycline sclerotherapy.…”

Section: Introductionmentioning

confidence: 99%

Comparison of endoscopic ultrasound-guided drainage and percutaneous drainage combined with minocycline sclerotherapy for symptomatic hepatic cysts: A retrospective study

Yoshimoto,

Takajo,

Iijima

et al. 2024

Medicine

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Simple hepatic cysts (SHC) are generally asymptomatic and incidentally diagnosed using imaging studies. Asymptomatic SHC does not require treatment, but symptomatic SHC warrants treatment using different modalities, including intravenous antibiotic therapy, ultrasound-guided percutaneous catheter drainage (PCD) with sclerotherapy, and surgery. The dissemination of endoscopic ultrasonography (EUS) intervention techniques has enabled the performance of puncture and drainage via the transgastrointestinal route for intra-abdominal abscesses. Despite the development of an EUS-guided drainage method for treating symptomatic SHC, only a few case reports using this method have been reported. This study retrospectively analyzed the safety and feasibility of EUS-guided drainage of symptomatic SHC as well as its clinical outcomes and compared it with combined therapy using PCD and minocycline sclerotherapy. The records of 10 consecutive patients with 11 symptomatic SHCs treated with either EUS-guided drainage or PCD combined with minocycline sclerotherapy at the Musashino Tokushukai Hospital from August 2019 to January 2024 were retrospectively examined. All cases in both groups achieved technical and clinical success, with no reported adverse events. The median reduction rates of the major cyst diameters in the EUS-guided drainage and PCD with sclerotherapy groups were 100% (interquartile range [IQR]: 94%–100%) and 67% (IQR: 48.5%–85%). The length of hospital stay was 7 and 22.5 days in the EUS-guided and PCD with sclerotherapy groups (P = .01). EUS-guided drainage of symptomatic SHC is a safe and effective therapeutic alternative to percutaneous drainage with sclerotherapy and surgery for treating symptomatic SHC.

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