Simple synthetic route to an enzyme-inspired transesterification catalyst

Abstract

Inspired by the chemical structure of chymotrypsin, we report an artificial catalytic triad with high catalytic efficiency for the transesterification reaction of vinyl trifluoroacetate and methanol. Rate accelerations of (kcat/kunc)...

Self-assembled prebiotic amphiphile-mixture exhibits tunable catalytic properties

“…The kinetic parameters were determined from the Michaelis-Menten equation, as reported earlier in similar systems. [32][33][34]58 The turnover rate (k cat ) was calculated to be 0.14 min −1 . Notably, OLH showed a catalytic efficiency (k cat /K M ) of 241 M −1 min −1 , which is comparable with previously reported systems (Table S1 †).…”