Simulation and analysis of 2D material/metal carbide based fiber optic SPR probe for ultrasensitive cortisol detection

Sharma, Anuj K.; Kaur, Baljinder; Marques, Carlos

doi:10.1016/j.ijleo.2020.164891

Cited by 26 publications

(13 citation statements)

References 23 publications

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“…Sharma et al reported that Ti 3 C 2 O 2 based probe can provide superior sensing of Cortisol with a detection limit of 15.7fg/mL. [84] This MXene based Cortisol sensor is relevant for real-time applications since it provides a non-invasive fiber optic surface plasmon resonance (FOSPR) based sensor probe to detect salivary Cortisol at the wavelength of 830 nm.…”

Section: Mxene Based Sensorsmentioning

confidence: 99%

MXene Based Sensing Materials: Current Status and Future Perspectives

Sivasankarapillai¹,

Sharma²,

Hwa³

et al. 2022

ES Energy Environ.

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MXenes are a family of two-dimensional multifunctional materials in a rapid development phase since their discovery in 2011. MXenes possess excellent features like high conductivity and surface area, improved mechanical properties, hydrophilicity, and ability to tune the surface properties with modifying functional groups. These features make MXenes suitable candidates for a wide range of applications, including biomedical and energy storage. This review is focused on various types of MXenes which are recently reported for sensor applications. The current scenario regarding fabrication and properties of MXenes are initially described, followed by a discussion of their applications as piezoresistive and biochemical sensors. This involves mechanical strain detection and detection of biomolecules, biomarkers, and drug molecules relevant to biomedical applications. Finally, the future perspectives are briefly discussed, which will help the researchers identify the limitations for the current scenario and develop new strategies that focus on developing novel, efficient and sensitive MXene based sensors.

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Section: Mxene Based Sensorsmentioning

confidence: 99%

MXene Based Sensing Materials: Current Status and Future Perspectives

Sivasankarapillai¹,

Sharma²,

Hwa³

et al. 2022

ES Energy Environ.

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Section: Stress Biomarkersmentioning

confidence: 99%

“…In 2020, Sharma et al [ 134 ] simulated an SPR fiber optic immunosensor for salivary cortisol detection at the wavelength of 830 nm. The sensor presented an Ag layer with 2D materials, conventional (graphene, tungsten disulfide (WS 2 ) and MoS 2 ) and transition metal carbides (MXenes: Ti 3 C 2 , Ti 3 C 2 O 2 , Ti 3 C 2 F 2 , Ti 3 C 2 (OH) 2 ) considered one at a time, which operated in two modes (‘AIM’ and ‘IIM’).…”

Section: Biosensing Applicationsmentioning

confidence: 99%

“…The sensor that showed a superior balanced set of performance parameters under both modes was the Ti 3 C 2 O 2 -based probe. Through the simulation, this probe was able to achieve an LOD of 15.7 fg·mL −1 [ 134 ]. Recently, Leitão et al [ 84 ] reported an SPR unclad POF immunosensor coated with gold/palladium (AuPd) alloy.…”

Section: Biosensing Applicationsmentioning

confidence: 99%

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Immunosensing Based on Optical Fiber Technology: Recent Advances

et al. 2021

Self Cite

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The evolution of optical fiber technology has revolutionized a variety of fields, from optical transmission to environmental monitoring and biomedicine, given their unique properties and versatility. For biosensing purposes, the light guided in the fiber core is exposed to the surrounding media where the analytes of interest are detected by different techniques, according to the optical fiber configuration and biofunctionalization strategy employed. These configurations differ in manufacturing complexity, cost and overall performance. The biofunctionalization strategies can be carried out directly on bare fibers or on coated fibers. The former relies on interactions between the evanescent wave (EW) of the fiber and the analyte of interest, whereas the latter can comprise plasmonic methods such as surface plasmon resonance (SPR) and localized SPR (LSPR), both originating from the interaction between light and metal surface electrons. This review presents the basics of optical fiber immunosensors for a broad audience as well as the more recent research trends on the topic. Several optical fiber configurations used for biosensing applications are highlighted, namely uncladded, U-shape, D-shape, tapered, end-face reflected, fiber gratings and special optical fibers, alongside practical application examples. Furthermore, EW, SPR, LSPR and biofunctionalization strategies, as well as the most recent advances and applications of immunosensors, are also covered. Finally, the main challenges and an outlook over the future direction of the field is presented.

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“…[263] In addition, with the further development of materials science, a variety of high-performance 2D materials, including transitionmetal dichalcogenide (TMDC), transition metal carbides, and hexagonal boron nitride are employed for sensing. [264][265][266] Among them, the application of TMDC to fiber SPR sensors has already been reported many times. In 2018, Wang et al utilized WS 2 nanosheets to modify the surface of the sensor, and compared with the case without WS 2 treatment, the sensitivity was increased by 26.6%.…”

Section: Introducing Novel Sensitive Materialsmentioning

confidence: 99%

Multichannel Fiber Optic SPR Sensors: Realization Methods, Application Status, and Future Prospects

Zhang

Han

Zhang

et al. 2022

Laser & Photonics Reviews

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Fiber optic sensors based on surface plasmon resonance (SPR) have demonstrated outstanding performance in biomedical, environmental monitoring, public safety, and other aspects, which provide powerful platforms for qualitative detection and quantitative analysis of molecular interactions. Among them, multichannel fiber optic SPR sensor has become a core tool in parallel detection scenarios due to the superiorities of compensating for nonspecific binding and environmental fluctuations and implementing multianalyte determination. The realization methods of multichannel sensing revolve around fiber microstructures, enhancement by materials, and hybrid fiber. The applications of multichannel fiber optic SPR sensors are demonstrated in sensing of liquid refractive index (RI), RI and temperature, biochemical molecules, and physical parameters. This review thoroughly analyzes and compares the structure, excitation effect, sensing performance, and the advantages and disadvantages of each type of multichannel fiber optic SPR sensor. Even though there are still some challenges, such as insufficient sensing channels and difficulty in fabrication, in their advancement, efforts in multidiscipline including developing high-performance sensitive films and innovating micro-nano fabrication processes will overcome these bottlenecks. Lastly, the future development directions of multichannel fiber optic SPR sensors from principle, structure, and material aspects are discussed.

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Simulation and analysis of 2D material/metal carbide based fiber optic SPR probe for ultrasensitive cortisol detection

Cited by 26 publications

References 23 publications

MXene Based Sensing Materials: Current Status and Future Perspectives

MXene Based Sensing Materials: Current Status and Future Perspectives

Immunosensing Based on Optical Fiber Technology: Recent Advances

Multichannel Fiber Optic SPR Sensors: Realization Methods, Application Status, and Future Prospects

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