The synchronicity of rain and heat in the summer of China’s monsoon region provides sufficient water and heat resources for maize growth. However, the intra-annual distribution of precipitation and the probability of extreme precipitation have been inevitably altered by the ongoing climate change, thus affecting the matching degree between precipitation and crop water requirements (MDPCWR). Evaluating the extent to which the MDPCWR will change in the future is of great importance for food security and the sustainable management of water resources. In this study, considering that different growth stages of crops have different sensitivities to water stress, the AquaCrop model was used to calculate the MDPCWR more accurately. In addition, a cumulative distribution function-transform (CDF-t) method was used to remove the bias of 11 global climate models (GCMs) under two typical emission scenarios (SSP2-4.5 and SSP5-8.5) from phase six of the Coupled Model Intercomparison Project (CMIP6). A comprehensive investigation was conducted on how maize growth, water consumption, and the MDPCWR will respond to future climate change with CO2 concentration enrichment in the Huang–Huai–Hai (3H) region in China by driving a well-tested AquaCrop model with the bias-corrected GCMs outputs. The results indicate the following: (1) The CDF-t method can effectively remove seasonal bias, and it also performs well in eliminating the bias of extreme climate events. (2) Under the SSP2-4.5 scenario, the average maximum temperature will increase by 1.31 °C and 2.44 °C in 2021–2050 and 2051–2080, respectively. The average annual precipitation will increase up to 96.8 mm/year, but it will mainly occur in the form of heavy rain. (3) The increased maize evapotranspiration rate does not compensate for the decreased crop water requirement (up to −32 mm/year), due to a shorter growth cycle. (4) The farmland cultivation layer is not able to hold a significant amount of precipitation, due to the increased frequency of heavy rains, resulting in increased irrigation water requirements for maize over the next two periods, with the maximum value of 12 mm/year. (5) Under different scenarios, the projected future MDPCWR will decrease by 9.3–11.6% due to changes in precipitation patterns and crop water requirements, indicating that it will be more difficult for precipitation to meet the water demand of maize growing in the 3H region. The results can provide comprehensive information to understand the impact of climate change on the agricultural water balance and improve the regional strategy for water resource utilization in the 3H region.