Simultaneous Bdellovibrio bacteriovorus–Bacteriophage dosing with SODIS for treatment of environmental water sources

Morris, Tinta Carmen; Reyneke, Brandon; Havenga, Benjamin; Khan, Sehaam; Khan, Wesaal

doi:10.1016/j.jece.2024.112359

Cited by 1 publication

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“…The synergistic or increased treatment efficiency that may be obtained when combining bacteriophage biocontrol with conventional treatment strategies is thus a crucial characteristic that highlights the potential of bacteriophages to eliminate microbial contaminants throughout the consumer water cycle ( Figure 1 B). Subsequently, the combination of bacteriophages with conventional antibiotics [ 25 , 26 ], chemical disinfectants [ 24 ], filtration systems [ 27 , 28 ], solar-based treatment [ 29 , 30 , 31 ], and the use of bacteriophages to enhance various industrial or water treatment processes have been investigated [ 12 , 32 ] (Outlined in Section 3 ). Additionally, while most biocontrol strategies are concentration-dependent and the treatment concentration may decrease after dosage, the bacteriophage treatment concentration will increase with time, as the bacteriophages continue to replicate and infect the target bacteria [ 15 ].…”

Section: Bacteriophage Characteristics Highlighting Their Potential A...mentioning

confidence: 99%

Benefits and Challenges of Applying Bacteriophage Biocontrol in the Consumer Water Cycle

Reyneke,

Havenga,

Waso-Reyneke

et al. 2024

Microorganisms

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Bacteria (including disinfection- and antibiotic-resistant bacteria) are abundant in the consumer water cycle, where they may cause disease, and lead to biofouling and infrastructure damage in distributions systems, subsequently resulting in significant economic losses. Bacteriophages and their associated enzymes may then offer a biological control solution for application within the water sector. Lytic bacteriophages are of particular interest as biocontrol agents as their narrow host range can be exploited for the targeted removal of specific bacteria in a designated environment. Bacteriophages can also be used to improve processes such as wastewater treatment, while bacteriophage-derived enzymes can be applied to combat biofouling based on their effectiveness against preformed biofilms. However, the host range, environmental stability, bacteriophage resistance and biosafety risks are some of the factors that need to be considered prior to the large-scale application of these bacterial viruses. Characteristics of bacteriophages that highlight their potential as biocontrol agents are thus outlined in this review, as well as the potential application of bacteriophage biocontrol throughout the consumer water cycle. Additionally, the limitations of bacteriophage biocontrol and corresponding mitigation strategies are outlined, including the use of engineered bacteriophages for improved host ranges, environmental stability and the antimicrobial re-sensitisation of bacteria. Finally, the potential public and environmental risks associated with large-scale bacteriophage biocontrol application are considered, and alternative applications of bacteriophages to enhance the functioning of the consumer water cycle, including their use as water quality or treatment indicators and microbial source tracking markers, are discussed.

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Section: Bacteriophage Characteristics Highlighting Their Potential A...mentioning

confidence: 99%

Benefits and Challenges of Applying Bacteriophage Biocontrol in the Consumer Water Cycle

Reyneke,

Havenga,

Waso-Reyneke

et al. 2024

Microorganisms

Self Cite

View full text Add to dashboard Cite

show abstract

Simultaneous Bdellovibrio bacteriovorus–Bacteriophage dosing with SODIS for treatment of environmental water sources

Cited by 1 publication

References 59 publications

Benefits and Challenges of Applying Bacteriophage Biocontrol in the Consumer Water Cycle

Benefits and Challenges of Applying Bacteriophage Biocontrol in the Consumer Water Cycle

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